重组食蟹猴CD47蛋白(Tagged) (ab271433)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 90% SDS-PAGE
- Tags: Avi tag C-Terminus, Fc tag C-Terminus
- Suitable for: WB, SDS-PAGE
描述
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产品名称
重组食蟹猴CD47蛋白(Tagged)
参阅全部 CD47 蛋白酶 -
纯度
>= 90 % SDS-PAGE. -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Cynomolgus monkey -
预测分子量
42 kDa including tags -
分子量信息
Protein runs at higher than predicted MW on SDS-PAGE due to glycosylation. -
氨基酸
19 to 139 -
标签
Avi tag C-Terminus , Fc tag C-Terminus -
额外的序列信息
Genbank: XM_015446485
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技术指标
Our Abpromise guarantee covers the use of ab271433 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 0.13% Sodium phosphate, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol (glycerin, glycerine)
常规信息
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别名
- Antigen identified by monoclonal antibody 1D8
- Antigenic surface determinant protein OA3
- CD 47
see all -
功能
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. -
组织特异性
Very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. -
序列相似性
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
细胞定位
Cell membrane. - Information by UniProt
图片
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SDS-PAGE - Recombinant CD47 protein (Tagged) (ab271433)SDS-PAGE analysis of ab271433.
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Size Exclusion Chromatography - Recombinant Cynomolgus monkey CD47 protein (Tagged) (ab271433)SEC analysis of ab271433.
Aggregation <10%.
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Western blot - Recombinant CD47 protein (Tagged) (ab271433)All lanes :
Lane 1 : ab271433
Lane 2 : MW markers
Predicted band size: 35 kDaWestern blot analysis of ab271433.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab271433 尚未被引用在任何文献中。