重组猫IL-2 (mutated C146S)蛋白(Active) (ab223097)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Tags: His tag N-Terminus
- Suitable for: Functional Studies, SDS-PAGE, MS
描述
-
产品名称
重组猫IL-2 (mutated C146S)蛋白(Active)
参阅全部 IL-2 蛋白酶 -
生物活性
Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is less or equal to 0.3 ng/ml.
-
纯度
> 95 % SDS-PAGE.
ab223097 was purified using conventional chromatography techniques. -
内毒素水平
< 1.000 Eu/µg -
表达系统
Escherichia coli -
Accession
-
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
-
种属
Cat -
序列
MGSSHHHHHHSSGLVPRGSHMGSAPASSSTKETQQQLEQLLLDLRLLLNG VNNPENPKLSRMLTFKFYVPKKATELTHLQCLVEELKPLEEVLYLAQSKN FHLNHIKELMSNINVTVLKLKGSETRFTCNYDDETATIVEFLNKWITFSQ SIFSTLT -
预测分子量
18 kDa including tags -
氨基酸
21 to 154 -
修饰
mutated C146 -
标签
His tag N-Terminus -
额外的序列信息
C146S mutation. This product is the mature full length protein from aa 21 to 154. The signal peptide is not included (NP_001036802).
-
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab223097 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
Functional Studies
SDS-PAGE
Mass Spectrometry
-
质谱法
MALDI-TOF -
形式
Liquid -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 30% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.32% Tris HClThis product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
-
别名
- Aldesleukin
- IL 2
- IL-2
see all -
功能
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. -
疾病相关
Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. -
序列相似性
Belongs to the IL-2 family. -
细胞定位
Secreted. - Information by UniProt
图片
-
SDS-PAGE - Recombinant cat IL-2 (mutated C146S) protein (Active) (ab223097)
15% SDS-PAGE analysis of 3 µg ab223097.
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab223097 尚未被引用在任何文献中。