PSD93多肽(ab5840)
Key features and details
- Purity: > 95% SDS-PAGE
- Suitable for: Blocking
描述
-
产品名称
PSD93多肽 -
纯度
> 95 % SDS-PAGE. -
无动物成分
No -
性质
Synthetic
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab5840 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
Blocking
-
形式
Lyophilized -
补充说明
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and PSD93, catalog ab2930. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.
-
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
-
复溶Reconstitute with 0.1 ml of distilled water.
常规信息
-
别名
- Channel associated protein of synapse 110
- Channel associated protein of synapses 110kD
- Channel-associated protein of synapse-110
see all -
功能
Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses. -
序列相似性
Belongs to the MAGUK family.
Contains 1 guanylate kinase-like domain.
Contains 3 PDZ (DHR) domains.
Contains 1 SH3 domain. -
结构域
An N-terminally truncated L27 domain is predicted in isoform 2 at positions 1 through 27. -
翻译后修饰
Palmitoylation of isoform 1 is not required for targeting to postsynaptic density. -
细胞定位
Cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Membrane. Cell projection, axon. Concentrated in soma and postsynaptic density of a subset of neurons. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (0)
ab5840 尚未被引用在任何文献中。
