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Native人PF4蛋白(ab81754)

Submit a review Q&A (2)
SDS-PAGE - Native human PF4 protein (ab81754)

    Key features and details

    • Expression system: Native
    • Purity: > 95% SDS-PAGE
    • Active: Yes
    • Suitable for: SDS-PAGE

    描述

    • 产品名称

      Native人PF4蛋白
      参阅全部 PF4 蛋白酶

    • 生物活性

      Specific Activity: Specific activity is determined by clotting assay. One unit will neutralize 1 I.U. of heparin in one milliliter of normal plasma. Min activity = 80 U/mg; Max activity = 134 U/mg.

    • 纯度

      > 95 % SDS-PAGE.

    • 表达系统

      Native

    • 蛋白长度

      Full length protein

    • 无动物成分

      No

    • 性质

      Native

      • 种属

        Human

      • 氨基酸

        32 to 101

    技术指标

    Our Abpromise guarantee covers the use of ab81754 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • 应用

      SDS-PAGE

    • 形式

      Liquid
    • Concentration information loading...

    制备和贮存

    • 稳定性和存储

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 7.40
      Constituents: 0.595% HEPES, 11.6% Sodium chloride

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    常规信息

    • 别名

      • C-X-C motif chemokine 4
      • Chemokine (C X C motif) ligand 4
      • Chemokine (CXC motif) ligand 4
      • chemokine ligand 4
      • CXCL 4
      • CXCL4
      • Iroplact
      • MGC138298
      • Oncostatin A
      • Oncostatin-A
      • OncostatinA
      • PF 4
      • PF-4
      • PF4
      • Pf4a
      • Platelet factor 4
      • PLF4_HUMAN
      • SCYB 4
      • SCYB4
      • short form
      • Small inducible cytokine subfamily B
      • Small inducible cytokine subfamily member 4
      see all

    • 功能

      Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.

    • 序列相似性

      Belongs to the intercrine alpha (chemokine CxC) family.

    • 翻译后修饰

      Binds non-covalently to a proteoglycan molecule.

    • 细胞定位

      Secreted.
    • Information by UniProt

    图片

    • SDS-PAGE - Native human PF4 protein (ab81754)
      SDS-PAGE - Native human PF4 protein (ab81754)
      SDS-PAGE analysis of ab81754 for 1ug protein.
      Novex 4-12% Bis-Tris Gel
      NR= non-reduced; R = reduced

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    文献 (0)

    发表研究结果有使用 ab81754？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab81754 尚未被引用在任何文献中。

    客户评价及客户问答

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    1-2 of 2 Abreviews or Q&A

    Question

    HIT stands for Heparin Induced Thrombocytopenia. We would like to detect HIT antibodies.
    Will you please answer our enquiry regarding the cost, time of delivery and cost for delivery to Greece?
    Thank you in advance
    Kind Regards

    Read More
    Answer

    Thank you very much for confirming the details.

    The product ab80477 is available for shipping. The cost is €465 plus €42 delivery charges. The product will be delivered by FedEX by overnight delivery.

    The product ab81754 is shipped in dry ice and we unfortunately do not ship dry ice products to Greece so this product will not be shipped.

    I have informed my colleague to send you a performa invoice; you will be receiving the invoice soon.

    I hope this info will be helpful. Should you have any question please do not hesitate to contact me.

    Read More

    Question

    Product code: 80477
    Inquiry: Dear sirs we are interested in buying the PF4 (human) native protein (cat number ab80477 or ab81754) for use in an ELISA assay for detection of HIT antibodies. Can you please verify if this is the correct product to use for the ELISA assay we are interested in? In addition will you please inform us of the cost of the product (including the delivery cost to Greece) and the time needed for delivery form the moment of ordering? Please note that we can arrange for a bank money transfer as soon as we receive a debit note, as a method of payment. Thank you in advance Kind Regards

    Read More
    Answer

    Thank you for contacting us.

    ELISA application is not tested with these products however because these are full length protein so these may be used.

    "ELISA assay for HIT detection" could you please explain how will be using these proteins and What is HIT?

    I will be lookingforward to hearing from you soon.

    Read More

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