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AB179799

NADPH oxidase 4多肽

NADPH oxidase 4 peptide

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(0 Publication)

NADPH oxidase 4 peptide is a Synthetic blocking peptide.

查看别名

RENOX, NOX4, NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase, KOX-1

关键信息

纯度

Whole antiserum

标签

Tag free

应用

BL

applications

生物活性

No

访问

Q9NPH5

不含动物源

No

不含载体蛋白

No

种属

Human

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "BL": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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产品详情

- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn't dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
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序列信息

[{"sequence":null,"proteinLength":null,"predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Synthetic","expressionSystem":null,"accessionNumber":"Q9NPH5","tags":[]}]
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性能和储存信息

运输条件
Blue Ice
推荐的短期储存时间
Up to 12 months
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
False
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特殊说明

形式

Liquid

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常规信息

功能

NADPH oxidase that catalyzes predominantly the reduction of oxygen to H2O2 (PubMed : 14966267, PubMed : 15356101, PubMed : 15927447, PubMed : 21343298, PubMed : 25062272). Can also catalyze to a smaller extent, the reduction of oxygen to superoxide (PubMed : 10869423, PubMed : 11032835, PubMed : 15155719, PubMed : 15572675, PubMed : 15927447, PubMed : 16019190, PubMed : 16179589, PubMed : 16230378, PubMed : 16324151, PubMed : 25062272). May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity (PubMed : 16019190). May regulate insulin signaling cascade (PubMed : 14966267). May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB (PubMed : 15356101, PubMed : 15572675). May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation (PubMed : 16324151).. Isoform 4. NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor (PubMed : 15721269, PubMed : 23393389). Involved in redox signaling in vascular cells (PubMed : 23393389). Modulates the nuclear activation of ERK1/2 and the ELK1 transcription factor, and is capable of inducing nuclear DNA damage (PubMed : 23393389).. Isoform 3. Lacks superoxide-generating NADPH oxidase activity.

翻译后修饰

Isoform 4. N-glycosylated and glycosylation is required for its proper function.. Isoform 3. N-glycosylated.

亚细胞定位

Nucleus

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

NADPH oxidase that catalyzes predominantly the reduction of oxygen to H2O2 (PubMed : 14966267, PubMed : 15356101, PubMed : 15927447, PubMed : 21343298, PubMed : 25062272). Can also catalyze to a smaller extent, the reduction of oxygen to superoxide (PubMed : 10869423, PubMed : 11032835, PubMed : 15155719, PubMed : 15572675, PubMed : 15927447, PubMed : 16019190, PubMed : 16179589, PubMed : 16230378, PubMed : 16324151, PubMed : 25062272). May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity (PubMed : 16019190). May regulate insulin signaling cascade (PubMed : 14966267). May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB (PubMed : 15356101, PubMed : 15572675). May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation (PubMed : 16324151).. Isoform 4. NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor (PubMed : 15721269, PubMed : 23393389). Involved in redox signaling in vascular cells (PubMed : 23393389). Modulates the nuclear activation of ERK1/2 and the ELK1 transcription factor, and is capable of inducing nuclear DNA damage (PubMed : 23393389).. Isoform 3. Lacks superoxide-generating NADPH oxidase activity.
See full target information NOX4
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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。
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关联产品

Select an associated product type
Alternative Product
Proteins & Peptides

AB155071

NADPH oxidase 4 peptide

proteins-peptides

nadph-oxidase-4-peptide-ab155071

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