mSin3A多肽(ab4995)
Key features and details
- Suitable for: Blocking
描述
-
产品名称
mSin3A多肽 -
无动物成分
No -
性质
Synthetic
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab4995 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
Blocking
-
形式
Liquid -
补充说明
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and the mouse mSin3A, catalog ab3479. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.
-
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
常规信息
-
别名
- AW553200
- DKFZP434K2235
- FLJ90319
see all -
功能
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST. -
序列相似性
Contains 3 PAH (paired amphipathic helix) domains. -
翻译后修饰
SUMO1 sumoylated by TOPORS. Probably desumoylated by SENP2. -
细胞定位
Nucleus. Nucleus > nucleolus. Recruited to the nucleolus by SAP30L. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (1)
ab4995 被引用在 1 文献中.
- Kudva AK et al. Gelatin microspheres releasing transforming growth factor drive in vitro chondrogenesis of human periosteum derived cells in micromass culture. Acta Biomater 90:287-299 (2019). PubMed: 30905864
