人XBP1多肽(ab39910)
Key features and details
- Purity: > 95% HPLC
- Suitable for: WB, Blocking
描述
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产品名称
人XBP1多肽 -
纯度
> 95 % HPLC. -
无动物成分
No -
性质
Synthetic -
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种属
Human
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab39910 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
Blocking
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA
常规信息
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别名
- Tax responsive element binding protein 5
- Tax-responsive element-binding protein 5
- TREB5
see all -
功能
Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I. -
疾病相关
Genetic variations in XBP1 could be associated with susceptibility to major affective disorder type 7 (MAFD7) [MIM:612371]. Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature. -
序列相似性
Belongs to the bZIP family.
Contains 1 bZIP domain. -
细胞定位
Nucleus. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab39910 尚未被引用在任何文献中。