人Gastrin多肽(ab42257)
Key features and details
- Purity: > 95% HPLC
- Suitable for: Blocking
描述
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产品名称
人Gastrin多肽
参阅全部 Gastrin 蛋白酶 -
纯度
> 95 % HPLC. -
无动物成分
No -
性质
Synthetic -
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种属
Human -
序列
Pyr-GPWLEEEEEAGWMDF -
氨基酸
77 to 92
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相关产品
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Corresponding Antibody
技术指标
Our Abpromise guarantee covers the use of ab42257 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Blocking - Blocking peptide for Anti-Gastrin antibody (ab14182)
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
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复溶Resuspend in 60% acetonitrile in 0.01M ammoiumbicarbonate for required concentration (vial content is 0.1 mg).
常规信息
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别名
- Component II
- G14
- G17
see all -
功能
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. -
序列相似性
Belongs to the gastrin/cholecystokinin family. -
翻译后修饰
Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.
Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific. -
细胞定位
Secreted. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab42257 尚未被引用在任何文献中。