人FLASH多肽(ab8455)
Key features and details
- Suitable for: Blocking, WB
描述
-
产品名称
人FLASH多肽 -
无动物成分
No -
性质
Synthetic -
-
种属
Human -
序列
SERFQQLMKLFEKSKC -
氨基酸
1966 to 1981
-
相关产品
-
Corresponding Antibody
技术指标
Our Abpromise guarantee covers the use of ab8455 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
Blocking - Blocking peptide for Anti-FLASH antibody (ab8420)
Western blot
-
形式
Liquid -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 7.20
Preservative: 0.02% Sodium azide
Constituent: 0.1% BSA
常规信息
-
别名
- AA387232
- C8AP2_HUMAN
- CASP 8 associated protein 2
see all -
功能
Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis. Required for histone gene transcription and progression through S phase. -
翻译后修饰
Phosphorylated upon DNA damage, probably by ATM or ATR. -
细胞定位
Cytoplasm. Nucleus. Localizes to discrete nuclear foci. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (0)
ab8455 尚未被引用在任何文献中。
