Active人TLR5多肽(ab40018)
Key features and details
- Active: Yes
- Suitable for: Blocking
描述
-
产品名称
Active人TLR5多肽
参阅全部 TLR5 蛋白酶 -
生物活性
TLR5 peptide is used for blocking the activity of TLR5 antibody ab37071. -
无动物成分
No -
性质
Synthetic -
-
种属
Human
-
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab40018 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
Blocking
-
形式
Liquid -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSAThis product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
-
别名
- FLJ10052
- MGC126430
- MGC126431
see all -
功能
Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. -
组织特异性
Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis. -
疾病相关
Systemic lupus erythematosus 1 -
序列相似性
Belongs to the Toll-like receptor family.
Contains 22 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain. -
翻译后修饰
Phosphorylated at Ser-805 by PKD/PRKD1; phosphorylation induces the production of inflammatory cytokines.
Phosphorylated at Tyr-798 upon flagellin binding; required for signaling. -
细胞定位
Membrane. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (0)
ab40018 尚未被引用在任何文献中。
