AB117837

Anti-ZNF787抗体

Name: ZNF787抗体 (ab117837)| Abcam中文官网
Brand: Abcam Limited
SKU: AB117837
Price: 4606 CNY
Availability: InStock

Anti-ZNF787 antibody

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(1 Publication)

Rabbit Polyclonal ZNF787 antibody. Suitable for IP, WB and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ZNF787 aa 1-50.

查看别名

Zinc finger protein 787, TTF-I-interacting peptide 20, ZNF787

2 Images

Unknown

Immunoprecipitation - Anti-ZNF787 antibody (AB117837)

Detection of Human ZNF787 by Immunoprecipitation in HeLa whole cell lysate (1 mg for IP, 20% of IP loaded) using ab117837 at 6 µg/mg of lysate. Subsequent WB detection was done using ab117837 at 1 µg/ml. ECL detection. Exposure time : 3 seconds.

All lanes:

Immunoprecipitation - Anti-ZNF787 antibody (ab117837)

Predicted band size: 40 kDa

false

Unknown

Western blot - Anti-ZNF787 antibody (AB117837)

All lanes:

Western blot - Anti-ZNF787 antibody (ab117837) at 0.04 µg/mL

Lane 1:

HeLa whole cell lysate at 50 µg

Lane 2:

HeLa whole cell lysate at 15 µg

Lane 3:

293T whole cell lysate at 50 µg

Lane 4:

Jurkat whole cell lysate at 50 µg

Lane 5:

NIH3T3 whole cell lysate at 50 µg

Predicted band size: 40 kDa

true

Exposure time: 3min

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Mouse, Human

应用

WB, IP

applications

免疫原

Synthetic Peptide within Human ZNF787 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

Q6DD87

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-10 µg/mg of lysate", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "" }, "Mouse": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "" }, "Rat": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Elephant": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Guinea pig": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

纯化说明

ab117837 was affinity purified using an epitope specific to ZNF787 immobilized on solid support.

存储溶液

pH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: 99% Tris buffered saline, 0.1% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

ZNF787 also known as Zinc Finger Protein 787 is a protein with a molecular mass of approximately 85 kDa. This protein is part of the zinc finger protein family which is characterized by the presence of zinc finger domains. These domains allow proteins to bind nucleic acids such as DNA and RNA influencing gene expression activities. ZNF787 is expressed in various tissues but shows significant expression in certain specific tissues like the brain and liver suggesting its role in organ-specific regulatory processes.

Biological function summary

Zinc Finger Protein 787 functions as a transcriptional regulator by influencing gene expression through DNA binding. It does not operate as part of a larger complex but acts independently to exert its regulatory functions. By binding to specific DNA sequences ZNF787 can promote or inhibit the expression of multiple genes which play roles in cell differentiation and proliferation. This suggests its possible involvement in key developmental and maintenance roles within an organism.

Pathways

Zinc Finger Protein 787 plays a role in genetic regulatory networks that impact the MAPK signaling pathway and the Wnt signaling pathway. In the MAPK pathway ZNF787 potentially modulates the transcription of genes influenced by MAPK-mediated phosphorylation events impacting cellular responses like growth and apoptosis. It may also interact with proteins such as MAPK and beta-catenin in these pathways thereby linking it to important signaling events in the cell.

Zinc Finger Protein 787 has been linked to certain cancer types such as liver cancer suggesting its potential role in tumorigenesis. Aberrations in the expression or function of ZNF787 may influence the regulation of oncogenes or tumor suppressor genes impacting the progression of cancer. Additionally irregularities in ZNF787 function have been associated with neurodegenerative diseases tying it to protein interactions involved in neuronal survival and health. Understanding ZNF787's specific interactions and regulatory mechanisms could therefore provide insights into these disease pathways potentially guiding therapeutic interventions.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

May be involved in transcriptional regulation.

See full target information ZNF787

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of cellular and molecular medicine 29:e70352 PubMed39855896

2025

Stromal Cell Derived Factor-1 Promotes Hepatic Insulin Resistance via Inhibiting Hepatocyte Lipophagy.

Applications

Unspecified application

Species

Unspecified reactive species

Chunfeng Lu,Yuting Zhang,Cuilian Sun,Yuhang Na,Haotian Sun,Jianhua Ma,Xueqin Wang,Xiaomin Cang

View all publications

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Anti-ZNF787抗体

Anti-ZNF787 antibody

Immunoprecipitation - Anti-ZNF787 antibody (AB117837)

Western blot - Anti-ZNF787 antibody (AB117837)