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AB180491

重组Anti-ZNF699抗体[EPR13383]

Anti-ZNF699 antibody [EPR13383]

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(1 Publication)

Rabbit Recombinant Monoclonal ZNF699 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

查看别名

Zinc finger protein 699, Hangover homolog, ZNF699

2 Images
Western blot - Anti-ZNF699 antibody [EPR13383] (AB180491)
  • WB

Supplier Data

Western blot - Anti-ZNF699 antibody [EPR13383] (AB180491)

All lanes:

Western blot - Anti-ZNF699 antibody [EPR13383] (ab180491) at 1/5000 dilution

Lane 1:

K562 cell lysate at 10 µg

Lane 2:

K562 cell lysate at 10 µg with immunizing peptide

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase Conjugate at 1/1000 dilution

Predicted band size: 73 kDa

Observed band size: 80 kDa

false

Western blot - Anti-ZNF699 antibody [EPR13383] (AB180491)
  • WB

Supplier Data

Western blot - Anti-ZNF699 antibody [EPR13383] (AB180491)

All lanes:

Western blot - Anti-ZNF699 antibody [EPR13383] (ab180491) at 1/20000 dilution

Lane 1:

Jurkat cell lysate at 20 µg

Lane 2:

K562 cell lysate at 20 µg

Lane 3:

U87-MG cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase Conjugate at 1/1000 dilution

Predicted band size: 73 kDa

Observed band size: 80 kDa

false

不同偶联物与剂型 (1)

  • Carrier free

    Anti-ZNF699 antibody [EPR13383] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR13383

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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产品详情

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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性能和储存信息

形式
Liquid
纯度
Tissue culture supernatant
存储溶液
Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

ZNF699 also known as Zinc Finger Protein 699 is a protein encoded by the ZNF699 gene in humans. This protein consists of zinc finger motifs which are small protein structural motifs able to bind to DNA. The molecular mass of ZNF699 is approximately 90 kDa. It is expressed in various tissues with high levels observed in the brain liver and kidney. The primary function of ZNF699’s zinc finger domains involves binding to specific DNA sequences influencing transcriptional regulation of target genes.
Biological function summary

Zinc finger proteins like ZNF699 play important roles in gene expression. ZNF699 does not appear to be part of any large multiprotein complex but interacts with a variety of other molecules involved in transcriptional regulation. It acts by binding to regulatory regions of genes influencing the transcription process. This interaction directly affects cellular functions such as proliferation differentiation and response to external signals. The precise biological role of ZNF699 remains under continued investigation but existing studies suggest a regulatory function in various cellular processes.

Pathways

ZNF699 is involved in transcriptional regulatory pathways that govern gene expression. It participates particularly in the Wnt signaling pathway which plays a significant role in embryonic development and cell growth. ZNF699’s interaction with other transcription factors such as TCF/LEF highlights its contribution in modulating gene expression within this signaling pathway. Additionally ZNF699 may cross-talk with the Hedgehog signaling pathway via interactions that influence cell fate decisions and morphogenesis.

Researchers associate ZNF699 with certain cancers and developmental disorders. Its dysregulation may contribute to tumorigenesis influencing the expression of oncogenes and tumor suppressor genes. In some cancers ZNF699 may interact aberrantly with proteins like p53 which is a well-known tumor suppressor. Additionally alterations in ZNF699 expression may also be linked to congenital malformations potentially through disrupted regulatory networks involving proteins like GLI1 a Hedgehog pathway component. Continued research will help to define the precise role of ZNF699 in these conditions and its potential as a therapeutic target.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

May be involved in transcriptional regulation.
See full target information Zinc finger protein 699
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of biological chemistry 300:107407 PubMed38796065

2024

Splice variants of CK1α and CK1α-like: Comparative analysis of subcellular localization, kinase activity, and function in the Wnt signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Tomáš Gybeľ,Štěpán Čada,Darja Klementová,Martin P Schwalm,Benedict-Tilman Berger,Marek Šebesta,Stefan Knapp,Vítězslav Bryja
View all publications
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