AB117803

Anti-ZNF687抗体

Name: ZNF687抗体 (ab117803)| Abcam中文官网
Brand: Abcam Limited
SKU: AB117803
Price: 4744 CNY
Availability: InStock

Anti-ZNF687 antibody

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(1 Publication)

Rabbit Polyclonal ZNF687 antibody. Suitable for IP and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ZNF687 aa 100-150.

查看别名

KIAA1441, ZNF687, Zinc finger protein 687

1 Images

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Immunoprecipitation - Anti-ZNF687 antibody (AB117803)

Lane 1 : Staining of ZNF687 in HeLa whole cell lysate immunoprecipitated using ab117803 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2 : control IgG. Predicted band size : 130 kDa. Exposure time : 3 minutes

All lanes:

Immunoprecipitation - Anti-ZNF687 antibody (ab117803)

Predicted band size: 129 kDa

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关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

applications

免疫原

Synthetic Peptide within Human ZNF687 aa 100-150. The exact immunogen used to generate this antibody is proprietary information.

Q8N1G0

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-10 µg/mg of lysate", "IP-species-notes": "<p></p>" }, "Baboon": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Chimpanzee": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Gorilla": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Rhesus monkey": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

纯化说明

ab117803 was affinity purified using an epitope specific to ZNF687 immobilized on solid support.

存储溶液

pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

ZNF687 also known as zinc finger protein 687 is a transcription factor with a known molecular mass of approximately 137 kDa. This protein contains multiple zinc finger motifs that enable its binding to specific DNA sequences regulating the transcription of certain genes. ZNF687 is expressed in various tissues including the brain liver and bone marrow. Its ability to bind DNA is critical for controlling gene expression related to cell proliferation and differentiation.

Biological function summary

ZNF687 functions as a regulatory protein involved in gene expression playing an important role in cellular growth and differentiation. It does not appear to be part of a larger protein complex but acts through binding to specific DNA sequences. The protein helps regulate genes involved in hematopoiesis and neural development suggesting a role in the development and maintenance of these tissues.

Pathways

ZNF687 contributes to gene transcription pathways important for cellular growth and development. It interfaces with signaling pathways such as the MAPK/ERK pathway which is significant for cell proliferation and survival. ZNF687 associates with other transcription factors and its function affects proteins like MYC and FOS which are central to these pathways. By regulating these pathways ZNF687 impacts cellular responses to internal and external stimuli.

ZNF687 is connected to several conditions including osteosarcoma and Paget's disease of bone. Mutations or dysregulation of ZNF687 have been implicated in these diseases potentially through interactions with proteins like SQSTM1 which plays a role in bone remodeling. Research continues to explore ZNF687's contributions to these conditions indicating its relevance in understanding and possibly targeting these diseases.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

May be involved in transcriptional regulation.

See full target information ZNF687

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of translational medicine 23:220 PubMed39985078

2025

SPICE1 promotes osteosarcoma growth by enhancing the deubiquitination of FASN mediated by USP10.

Applications

Unspecified application

Species

Unspecified reactive species

Weilai Tong,Xinsheng Xie,Zhiguo Shu,Jiangbo Nie,Xianhe Yang,Feng Yang,Zhili Liu,Jiaming Liu

View all publications

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Anti-ZNF687抗体

Anti-ZNF687 antibody

Immunoprecipitation - Anti-ZNF687 antibody (AB117803)