Anti-ZIP-5抗体(ab105194)
Key features and details
- Rabbit polyclonal to ZIP-5
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-ZIP-5抗体 -
描述
兔多克隆抗体to ZIP-5 -
宿主
Rabbit -
特异性
ab105194 is predicted not to cross-react with other ZIP family members. -
经测试应用
适用于: ICC/IF, WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Synthetic peptide corresponding to Human ZIP-5 (internal sequence).
Database link: NP_001128667 -
阳性对照
- Human spleen tissue lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab105194于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC/IF |
Use a concentration of 20 µg/ml.
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| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa.
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| IHC-P |
Use at an assay dependent concentration.
|
| 说明 |
|---|
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ICC/IF
Use a concentration of 20 µg/ml. |
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa. |
|
IHC-P
Use at an assay dependent concentration. |
靶标
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功能
May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera (PubMed:24891338). Seems to play a central role in controlling organismal zinc status. -
组织特异性
Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney. -
疾病相关
Myopia 24, autosomal dominant -
序列相似性
Belongs to the ZIP transporter (TC 2.A.5) family. -
翻译后修饰
Glycosylated. -
细胞定位
Basolateral cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 283375 Human
- Entrez Gene: 72002 Mouse
- GenBank: NM_173596 Human
- Omim: 608730 Human
- SwissProt: Q6ZMH5 Human
- SwissProt: Q9D856 Mouse
- Unigene: 591018 Human
- Unigene: 22983 Mouse
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别名
- LZT Hs7 antibody
- MGC34778 antibody
- OTTHUMP00000211153 antibody
see all
图片
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Western blot - Anti-ZIP-5 antibody (ab105194)Anti-ZIP-5 antibody (ab105194) at 1 µg/ml + Human spleen tissue lysate at 15 µg
Predicted band size: 56 kDa -
Immunocytochemistry/ Immunofluorescence - Anti-ZIP-5 antibody (ab105194)Immunofluorescence of ZIP-5 in Human spleen tissue with ab105194 at 20 ug/mL.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZIP-5 antibody (ab105194)Immunohistochemistry of ZIP-5 in Human spleen tissue with ab105194 at 2.5 μg/mL.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab105194 被引用在 1 文献中.
- Hu Y et al. The organic zinc with moderate chelation strength enhances the expression of related transporters in the jejunum and ileum of broilers. Poult Sci 102:102477 (2023). PubMed: 36680861