AB117787

Anti-ZFP64抗体

Name: ZFP64抗体 (ab117787)| Abcam中文官网
Brand: Abcam Limited
SKU: AB117787
Price: 4606 CNY
Availability: InStock

Anti-ZFP64 antibody

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(1 Publication)

Rabbit Polyclonal ZFP64 antibody. Suitable for IP, WB and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ZFP64 aa 400-450.

查看别名

ZNF338, ZFP64, Zinc finger protein 64, Zfp-64, Zinc finger protein 338

2 Images

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Immunoprecipitation - Anti-ZFP64 antibody (AB117787)

Detection of ZFP64 by Western Blot of Immunprecipitate.
ab117787 at 1µg/ml staining ZFP64 in 293T whole cell lysate immunoprecipitated using ab117787 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
Detection : Chemiluminescence with exposure time of 30 seconds.

All lanes:

Immunoprecipitation - Anti-ZFP64 antibody (ab117787)

Predicted band size: 74 kDa

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Western blot - Anti-ZFP64 antibody (AB117787)

All lanes:

Western blot - Anti-ZFP64 antibody (ab117787) at 0.04 µg/mL

Lane 1:

293T whole cell lysates at 50 µg

Lane 2:

293T whole cell lysates at 15 µg

Lane 3:

Jurkat whole cell lysates at 50 µg

Lane 4:

HeLa whole cell lysates at 50 µg

Lane 5:

NIH 3T3 whole cell lysates at 50 µg

Predicted band size: 74 kDa

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Exposure time: 3min

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Mouse, Human

应用

WB, IP

applications

免疫原

Synthetic Peptide within Human ZFP64 aa 400-450. The exact immunogen used to generate this antibody is proprietary information.

Q9NTW7

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-10 µg/mg of lysate", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "" }, "Mouse": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "" }, "Rat": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chimpanzee": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Ferret": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Guinea pig": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rabbit": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

纯化说明

ab117787 was affinity purified using an epitope specific to ZFP64 immobilized on solid support.

存储溶液

pH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: 99% Tris buffered saline, 0.1% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

ZFP64 also known as Zinc Finger Protein 64 acts as a transcription factor with a molecular mass of approximately 71 kDa. This protein contains multiple zinc finger domains and is highly expressed in various tissues including the brain liver and lymphoid tissues. ZFP64 regulates the transcription of target genes by binding to specific DNA sequences influencing gene expression patterns in cells.

Biological function summary

Zinc Finger Protein 64 is involved in critical cellular processes such as cell differentiation and proliferation. It contributes to gene regulation in the context of chromatin remodeling complexes but not as a direct component. ZFP64 plays significant roles in immune response modulation and neural development affecting both protein coding and non-coding regions of the genome. Research has shown its involvement in T-cell regulation and neuronal lineage determination.

Pathways

Zinc Finger Protein 64 plays an important role in the Wnt signaling pathway and the NF-kB signaling pathway. In the Wnt signaling pathway ZFP64 interacts with other proteins to control cellular processes such as growth and migration. In the NF-kB pathway ZFP64 cooperates with other transcription factors to regulate inflammatory responses and immune system activation interacting with proteins such as IKK and RelA in the process.

Research connects Zinc Finger Protein 64 to the development of autoimmune diseases and certain types of cancer such as leukemia. Alterations in ZFP64 expression or mutations may impact the regulation of immune genes leading to uncontrolled immune responses or tumor progression. The protein is also linked to aberrations in the activity of MYC in cancerous conditions influencing the cell cycle and apoptosis pathways.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

May be involved in the regulation of mesenchymal cell differentiation through transactivation of NOTCH1 target genes.

See full target information ZFP64

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Antioxidants (Basel, Switzerland) 12: PubMed37627542

2023

Quercetin's Dual Mode of Action to Counteract the Sp1-miR-27a Axis in Colorectal Cancer Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Emanuele Fosso,Manuela Leo,Livio Muccillo,Vittorio Maria Mandrone,Maria Chiara Di Meo,Annamaria Molinario,Ettore Varricchio,Lina Sabatino

View all publications

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Anti-ZFP64抗体

Anti-ZFP64 antibody

Immunoprecipitation - Anti-ZFP64 antibody (AB117787)

Western blot - Anti-ZFP64 antibody (AB117787)