Anti-XRN2抗体(ab74408)
Key features and details
- Rabbit polyclonal to XRN2
- Suitable for: IHC-P, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-XRN2抗体
参阅全部 XRN2 一抗 -
描述
兔多克隆抗体to XRN2 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ICC/IFmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Chimpanzee, Rhesus monkey, Orangutan, Bat, Elephant
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免疫原
Synthetic peptide corresponding to Human XRN2. Synthetic peptide corresponding to a region between residues 900 and 950 human XRN2 (NP_036387.2).
Database link: Q9H0D6 -
阳性对照
- Human tissues: Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Non Small Cell Lung Cancer, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Prostate Carcinoma, Skin Basal Cell Carcinoma, Small Cell Lung Cancer, Stomach Adenocarcinoma, Testicular Seminoma. Mouse tissues: Colon Carcinoma CT26, Teratoma.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab74408 was affinity purified using an epitope specific to XRN2 immobilized on solid support. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab74408于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/100 - 1/500.
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| ICC/IF |
1/100.
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| 说明 |
|---|
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IHC-P
1/100 - 1/500. |
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ICC/IF
1/100. |
靶标
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相关性
XRN2 possesses 5'->3' exoribonuclease activity. XRN2 shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The function of the human gene has not yet been determined, however, it may promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. -
细胞定位
Nucleus, nucleolus. -
数据库链接
- Entrez Gene: 22803 Human
- Entrez Gene: 24128 Mouse
- Omim: 608851 Human
- SwissProt: Q9H0D6 Human
- SwissProt: Q9DBR1 Mouse
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别名
- 5' 3' exoribonuclease 2 antibody
- DHM1 like protein antibody
- DHP protein antibody
- XRN 2 antibody
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-XRN2 antibody (ab74408)ab74408, at 1/250 dilution, staining XRN2 in formalin fixed, paraffin embedded human breast carcinoma tissue by Immunohistochemistry. Detection: DAB staining.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-XRN2 antibody (ab74408)ab74408, at 1/250 dilution, staining XRN2 in formalin fixed, paraffin embedded human ovarian carcinoma tissue by Immunohistochemistry. Detection: DAB staining. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-XRN2 antibody (ab74408)ab74408, at 1/250 dilution, staining XRN2 in formalin fixed, paraffin embedded mouse teratoma tissue by Immunohistochemistry. Detection: DAB staining. -
Immunocytochemistry/ Immunofluorescence - Anti-XRN2 antibody (ab74408)ab74408, at 1/100 dilution, staining XRN2 in human breast carcinoma tissue by Immunofluorescence. Detection: Red fluorescent Alexa Fluor 555 goat anti rabbit IgG at 1/500.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab74408 尚未被引用在任何文献中。