JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB270320

重组Anti-XCL1抗体[EPR22634-115] - BSA and Azide free (Capture)

Anti-XCL1 antibody [EPR22634-115] - BSA and Azide free (Capture)

Be the first to review this product! Submit a review

|

(0 Publication)

Rabbit Recombinant Monoclonal XCL1 antibody. Carrier free. Suitable for sELISA and reacts with Mouse samples.

查看别名

Lptn, Ltn, Scyc1, Xcl1, Lymphotactin, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, Small-inducible cytokine C1

1 Images
Sandwich ELISA - Anti-XCL1 antibody [EPR22634-115] - BSA and Azide free (Capture) (AB270320)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-XCL1 antibody [EPR22634-115] - BSA and Azide free (Capture) (AB270320)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab269540).

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR22634-115

亚型

IgG

不含载体蛋白

Yes

反应种属

Mouse

应用

sELISA

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
style
left-column

产品详情

ab270320 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Mouse XCL1. The recommended pair for sandwich ELISA is:
Capture: ab270320, Mouse XCL1 Capture Antibody (unconjugated)
Detector: ab270321, Mouse XCL1 Detector Antibody (unconjugated)
The reference range value is 18.75 - 1200 pg/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

style
left-column

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
Constituents: PBS
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
+4°C
style
left-column

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

XCL1 also known as lymphotactin is a chemokine with a molecular mass of approximately 10 kDa. This protein plays a role in the immune system directing the movement of cells such as T lymphocytes to sites of inflammation or infection. XCL1 is mainly expressed in activated T cells natural killer cells and some other immune cells. Its expression gets upregulated in response to certain stimuli which helps to recruit additional immune effector cells to areas where they are needed.
Biological function summary

XCL1 participates in chemotaxis guiding the migration of specific cells to enhance the immune response. Although XCL1 does not form part of a larger protein complex it interacts with its specific receptor XCR1 on target cells. This interaction triggers intracellular signaling pathways contributing to the controlled movement and positioning of immune cells in response to infection or inflammatory signals.

Pathways

XCL1 is significantly involved in the chemokine signaling pathway and plays a part in immune response regulation. This pathway shared with other chemokines like CCL2 and CCL5 orchestrates the precise movement and activity of immune cells. XCL1’s interaction with XCR1 is central to initiating downstream signaling processes which influence immune responses and inflammation.

XCL1 associates with autoimmune diseases and certain viral infections. Its dysregulation appears in conditions such as rheumatoid arthritis where the abnormal control of immune cells contributes to inflammation and tissue damage. In viral infections like HIV XCL1 helps modulate immune cell responses against the virus. XCR1 the receptor of XCL1 also plays a role in these diseases being a critical component in mediating the effects of lymphotactin in varied pathological contexts.
style
left-column
style
left-column

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

靶点信息

Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
See full target information Xcl1
style
left-column
style
left-column
style
right-column

搭配使用产品

Assay Kits

AB264620

Human XCL1 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human XCL1 ELISA Kit (AB264620)

  • 0
  • 0
Primary Antibodies

AB302522

Anti-XCL1+XCL2 antibody [EPR26181-30]

20ul selling size|RabMAb|Recombinant

Immunocytochemistry - Anti-XCL1+XCL2 antibody [EPR26181-30] (AB302522)

  • 0
  • 0
Sample Prep & Detection Kits

AB102918

PE / R-Phycoerythrin Conjugation Kit - Lightning-Link®

Flow Cytometry - PE / R-Phycoerythrin Conjugation Kit - Lightning-Link® (AB102918)

  • 5
  • 2
Primary Antibodies

AB37407

PE-Rabbit IgG - Isotype Control

  • 0
  • 0
Primary Antibodies

AB225864

Anti-GC-C antibody [EPR22056-278]

RabMAb|Recombinant|Trial Size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GC-C antibody [EPR22056-278] (AB225864)

  • 0
  • 0

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com