Anti-WWC2抗体(ab126356)
Key features and details
- Rabbit polyclonal to WWC2
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-WWC2抗体 -
描述
兔多克隆抗体to WWC2 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
antigen sequence corresponding to amino acids 784-884 of Human WWC2.
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阳性对照
- Human testis tissue
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab126356于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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| 说明 |
|---|
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
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ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
靶标
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序列相似性
Belongs to the WWC family.
Contains 1 C2 domain.
Contains 2 WW domains. - Information by UniProt
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数据库链接
- Entrez Gene: 80014 Human
- SwissProt: Q6AWC2 Human
- Unigene: 333179 Human
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别名
- BH-3-only member B antibody
- BH3 only member B protein antibody
- BOMB antibody
see all
图片
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Immunocytochemistry/ Immunofluorescence - Anti-WWC2 antibody (ab126356)Immunofluorescent staining of Human cell line U-2 OS shows positivity in cytoskeleton (microtubules). Recommended concentration of ab126356 1-4 µg/ml. Cells treated with PFA/Triton X-100.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-WWC2 antibody (ab126356)ab126356, at 1/50 dilution, staining WWC2 in paraffin-embedded Human testis tissue by Immunohistochemistry.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab126356 被引用在 3 文献中.
- Qi S et al. Two Hippo signaling modules orchestrate liver size and tumorigenesis. EMBO J 42:e112126 (2023). PubMed: 36919851
- Yuan B et al. Down-Regulation of LINC00460 Represses Metastasis of Colorectal Cancer via WWC2. Dig Dis Sci 65:442-456 (2020). PubMed: 31541369
- Zhang Y et al. WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma. J Cell Mol Med 21:3718-3729 (2017). IHC-P ; Human . PubMed: 28815883