Anti-Wnt1抗体(ab63934)
Key features and details
- Rabbit polyclonal to Wnt1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Wnt1抗体
参阅全部 Wnt1 一抗 -
描述
兔多克隆抗体to Wnt1 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide surrounding amino acid 31 of human Wnt1
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阳性对照
- WB: Jurkat cell lysate.
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常规说明
This product is manufactured by BioVision, an Abcam company and was previously called 3571 Anti-Wnt-1 Antibody. 3571-100 is the same size as the 100 µg size of ab63934.
Wnt1 antibody has been purified by Protein A/G combination.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA -
Concentration information loading... -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab63934于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.5 - 4 µg/ml. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
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| 说明 |
|---|
|
WB
Use a concentration of 0.5 - 4 µg/ml. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa). |
靶标
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功能
Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters. -
序列相似性
Belongs to the Wnt family. -
细胞定位
Secreted > extracellular space > extracellular matrix. - Information by UniProt
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数据库链接
- Entrez Gene: 7471 Human
- Omim: 164820 Human
- SwissProt: P04628 Human
- Unigene: 248164 Human
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别名
- BMND16 antibody
- INT1 antibody
- OI15 antibody
see all
图片
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Western blot - Anti-Wnt1 antibody (ab63934)All lanes : Anti-Wnt1 antibody (ab63934) at 1 µg/ml
All lanes : Jurkat cell lysate
Lysates/proteins at 35 µg per lane.
Predicted band size: 41 kDa
Observed band size: 41 kDa
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab63934 被引用在 6 文献中.
- Marcogliese PC et al. Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling. Sci Adv 8:eabl5613 (2022). PubMed: 35044823
- Jiang H et al. lncRNAS56464.1 as a ceRNA promotes the proliferation of fibroblast-like synoviocytes in experimental arthritis via the Wnt signaling pathway and sponges miR-152-3p. Int J Mol Med 47:N/A (2021). PubMed: 33448322
- Ortega MA et al. Abnormal proinflammatory and stressor environmental with increased the regulatory cellular IGF-1/PAPP-A/STC and Wnt-1/β-Catenin canonical pathway in placenta of women with Chronic venous Disease during Pregnancy. Int J Med Sci 18:2814-2827 (2021). PubMed: 34220309
- Chen L et al. Role of lncRNA BCYRN1 in trophoblast cell physiology and pathogenesis of preeclampsia. Exp Ther Med 22:1137 (2021). PubMed: 34466147
- Liu MM et al. Therapeutic potential of Liuwei Dihuang pill against KDM7A and Wnt/ß-catenin signaling pathway in diabetic nephropathy-related osteoporosis. Biosci Rep 40:N/A (2020). PubMed: 32914833
- Kim NH et al. p53 and microRNA-34 are suppressors of canonical Wnt signaling. Sci Signal 4:ra71 (2011). WB . PubMed: 22045851