JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB177480

重组Anti-Versican抗体[EPR12277]

Anti-Versican antibody [EPR12277]

4

(3 Reviews)

|

(34 Publications)

Rabbit Recombinant Monoclonal Versican antibody. Suitable for WB and reacts with Mouse, Rat, Human samples. Cited in 34 publications.

查看别名

CSPG2, VCAN, Versican core protein, Chondroitin sulfate proteoglycan core protein 2, Glial hyaluronate-binding protein, Large fibroblast proteoglycan, PG-M, Chondroitin sulfate proteoglycan 2, GHAP

2 Images
Western blot - Anti-Versican antibody [EPR12277] (AB177480)
  • WB

Unknown

Western blot - Anti-Versican antibody [EPR12277] (AB177480)

Blocking and diluting buffer : 5% NFDM/TBST

This antibody detects multi-bands due to the splicing variants and proteolytic fragments (PMID : 27683612, 24401530, 29222454, 19662655)

All lanes:

Western blot - Anti-Versican antibody [EPR12277] (ab177480) at 0.1 µg/mL

Lane 1:

Human hippocampus lysate at 20 µg

Lane 2:

Mouse hippocampus lysates at 20 µg

Lane 3:

Mouse heart lysates at 20 µg

Lane 4:

Rat hippocampus lysates at 20 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/20000 dilution

Predicted band size: 373 kDa

false

Western blot - Anti-Versican antibody [EPR12277] (AB177480)
  • WB

Supplier Data

Western blot - Anti-Versican antibody [EPR12277] (AB177480)

All lanes:

Western blot - Anti-Versican antibody [EPR12277] (ab177480) at 1/1000 dilution

Lane 1:

Fetal brain lysate at 10 µg

Lane 2:

Fetal heart lysate at 10 µg

Predicted band size: 373 kDa

false

不同偶联物与剂型 (1)

  • Carrier free

    Anti-Versican antibody [EPR12277] - BSA and Azide free

关键信息

宿主种属

Rabbit

克隆

Monoclonal

克隆号

EPR12277

亚型

IgG

不含载体蛋白

No

反应种属

Mouse, Rat, Human

应用

WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "1/50 - 1/100", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "1/50 - 1/100", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "1/50 - 1/100", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." } } }

产品详情

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Protein A
存储溶液
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

靶点信息

May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.
See full target information VCAN

文献 (34)

Recent publications for all applications. Explore the full list and refine your search

Nature cardiovascular research 4:1066-1076 PubMed40866626

2025

Human ocular fluid outflow on-chip reveals trabecular meshwork-mediated Schlemm's canal endothelial dysfunction in steroid-induced glaucoma.

Applications

Unspecified application

Species

Unspecified reactive species

Renhao Lu,Anna M Kolarzyk,W Daniel Stamer,Esak Lee

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 73:129-145 PubMed40219589

2025

Localization, Proteolytic Processing, and Binding Partners of Versican Isoforms in Vascular Lesions of Pulmonary Arterial Hypertension.

Applications

Unspecified application

Species

Unspecified reactive species

Christian Westöö,Ayse Ceren Mutgan,Oscar van der Have,Timothy J Mead,Salaheldin Ahmed,Elna Lampei,Christopher D Koch,Christian Norvik,Anders Aspberg,Martin Bech,Niccolò Peruzzi,Hans Brunnström,Grazyna Kwapiszewska,Göran Rådegran,Suneel S Apte,Karin Tran-Lundmark

Journal for immunotherapy of cancer 12: PubMed39448202

2024

Targeting CD93 on monocytes revitalizes antitumor immunity by enhancing the function and infiltration of CD8 T cells.

Applications

Unspecified application

Species

Unspecified reactive species

Da Jiang,Aiqi Huang,Bai-Xi Zhu,Jiangling Gong,Yong-Hao Ruan,Xing-Chen Liu,Limin Zheng,Yan Wu

The European journal of neuroscience 60:6490-6508 PubMed39410873

2024

Pramipexole, a D3 receptor agonist, increases cortical gamma power and biochemical correlates of cortical excitation; implications for mood disorders.

Applications

Unspecified application

Species

Unspecified reactive species

Karli F Gilbert,Matthew Amontree,Samantha Deasy,Junfeng Ma,Katherine Conant

eLife 13: PubMed38980810

2024

Tumor purity-related genes for predicting the prognosis and drug sensitivity of DLBCL patients.

Applications

Unspecified application

Species

Unspecified reactive species

Zhenbang Ye,Ning Huang,Yongliang Fu,Rongle Tian,Liming Wang,Wenting Huang

Journal of pharmaceutical analysis 14:335-347 PubMed38618242

2024

Hapln1 promotes dedifferentiation and proliferation of iPSC-derived cardiomyocytes by promoting versican-based GDF11 trapping.

Applications

Unspecified application

Species

Unspecified reactive species

Ding-Jun Hao,Yue Qin,Shi-Jie Zhou,Bu-Huai Dong,Jun-Song Yang,Peng Zou,Li-Ping Wang,Yuan-Ting Zhao

Heliyon 9:e18698 PubMed37554815

2023

Lnc-PLA2G4A-4 facilitates the progression of hepatocellular carcinoma by inducing versican expression via sponging miR-23b-3p.

Applications

Unspecified application

Species

Unspecified reactive species

Jiahui Xiong,Yongping Lai,Niangmei Cheng,Jizhe Liu,Fei Wang,Xiaoyuan Zheng,Yingchao Wang,Qiuyu Zhuang,Yantin Lin,Jingfeng Liu,Yixuan Yang,Bixing Zhao,Xiaoyu Yang

Materials today. Bio 22:100731 PubMed37533731

2023

Injectable mesoporous bioactive glass/sodium alginate hydrogel loaded with melatonin for intervertebral disc regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Ruibang Wu,Leizhen Huang,Qinghong Xia,Zheng Liu,Yong Huang,Yulin Jiang,Juehan Wang,Hong Ding,Ce Zhu,Yueming Song,Limin Liu,Li Zhang,Ganjun Feng

Disease markers 2022:6595778 PubMed36569220

2022

Prognostic Biomarkers Identification in Esophageal Cancer Based on WGCNA and Single-Cell Analysis.

Applications

Unspecified application

Species

Unspecified reactive species

Wen-Jun Zhao,Yao Liu,Jing Guo,Hua Liu

Frontiers in immunology 13:960570 PubMed36203562

2022

Versican enrichment predicts poor prognosis and response to adjuvant therapy and immunotherapy in gastric cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Junquan Song,Rongyuan Wei,Shiying Huo,Chenchen Liu,Xiaowen Liu
View all publications

Abcam Product Promise

我们致力于为您的研究提供高质量的试剂,为您科研的每一步提供支持。若我们的产品未能达到预期性能,我们向您提供 Abcam Product Promise 保障。
详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com