Anti-Vasopressin抗体(ab68669)
Key features and details
- Rabbit polyclonal to Vasopressin
- Suitable for: IHC-P, ELISA
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Vasopressin抗体
参阅全部 Vasopressin 一抗 -
描述
兔多克隆抗体to Vasopressin -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ELISAmore details
不适用于: WB -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Sheep, Cow, Cat, Dog, Pig
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免疫原
Synthetic peptide corresponding to Human Vasopressin aa 1-100 conjugated to keyhole limpet haemocyanin.
(Peptide available asab68668) -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 98.98% PBS, 1% BSA
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab68669于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 1 - 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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| ELISA |
Use a concentration of 0.002 µg/ml.
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| 说明 |
|---|
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IHC-P
Use a concentration of 1 - 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
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ELISA
Use a concentration of 0.002 µg/ml. |
应用说明
Is unsuitable for WB.
靶标
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相关性
Vasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a posterior pituitary hormone that is synthesised in the hypothalamus. Vasopressin is synthesised as a precursor protein that consists of arginine vasopressin and two associated proteins, neurophysin 2 and the glycopeptide copeptin. Vasopressin, together with its carrier protein neurophysin II, is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. Vasopressin can also contract smooth muscle during parturition and lactation. It also plays a role in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in the vasopressin precursor cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI), which is characterised by persistant thirst, polydipsia and polyuria. -
细胞定位
Secreted -
数据库链接
- Entrez Gene: 280728 Cow
- Entrez Gene: 403579 Dog
- Entrez Gene: 551 Human
- Entrez Gene: 11998 Mouse
- Entrez Gene: 396995 Pig
- Entrez Gene: 24221 Rat
- Omim: 192340 Human
- SwissProt: P01180 Cow
see all -
别名
- ADH antibody
- Antidiuretic hormone antibody
- Arginine vasopressin neurophysin II antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Vasopressin antibody (ab68669)IHC image of Vasopressin staining in human Hippocampus FFPE section, performed on a BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab68669 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX
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ELISA - Anti-Vasopressin antibody (ab68669)ELISA using ab68669 at varying antibody concentrations. The black line indicates binding to the vasopressin peptide ab68668.
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab68669 被引用在 4 文献中.
- Belity T et al. Heat-Stress Preconditioning Attenuates Behavioral Responses to Psychological Stress: The Role of HSP-70 in Modulating Stress Responses. Int J Mol Sci 23:N/A (2022). PubMed: 35456946
- Cheng W et al. Paraventricular Nucleus P2X7 Receptors Aggravate Acute Myocardial Infarction Injury via ROS-Induced Vasopressin-V1b Activation in Rats. Neurosci Bull 37:641-656 (2021). PubMed: 33620697
- Danan D et al. Is PTSD-Phenotype Associated with HPA-Axis Sensitivity? Feedback Inhibition and Other Modulating Factors of Glucocorticoid Signaling Dynamics. Int J Mol Sci 22:N/A (2021). PubMed: 34205191
- Zhou ZB et al. Sevoflurane-induced down-regulation of hippocampal oxytocin and arginine vasopressin impairs juvenile social behavioral abilities. J Mol Neurosci 56:70-7 (2015). IHC . PubMed: 25417719