Anti-Varicella Zoster Virus gI抗体[8C4] (ab52552)
Key features and details
- Mouse monoclonal [8C4] to Varicella Zoster Virus gI
- Suitable for: ICC/IF, WB, ELISA
- Reacts with: Varicella zoster virus
- Isotype: IgG1
概述
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产品名称
Anti-Varicella Zoster Virus gI抗体[8C4] -
描述
小鼠单克隆抗体[8C4] to Varicella Zoster Virus gI -
宿主
Mouse -
经测试应用
适用于: ICC/IF, WB, ELISAmore details -
种属反应性
与反应: Varicella zoster virus -
免疫原
Tissue, cells or virus corresponding to Varicella Zoster Virus gI.
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阳性对照
- WB: VZV infected cells. ICC/IF: VZV human fibroblast slides.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
8C4 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab52552于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ICC/IF |
1/1600.
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WB |
1/400. Detects a band of approximately 54 kDa (predicted molecular weight: 39 kDa).
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ELISA |
1/51200.
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说明 |
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ICC/IF
1/1600. |
WB
1/400. Detects a band of approximately 54 kDa (predicted molecular weight: 39 kDa). |
ELISA
1/51200. |
靶标
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相关性
The Varicella zoster virus (VZV) is one of the eight herpes viruses known to affect humans (and other vertebrates). Primary VZV infection results in chickenpox (varicella), which may rarely result in complications including VZV encephalitis or pneumonia. Glycoprotein I (gI) of varicella-zoster virus (VZV) contributes to viral virulence and is a potentially important target for T cell control of viral replication. -
细胞定位
Cell Membrane; single pass type I membrane protein -
别名
- GI antibody
- Glycoprotein IV antibody
- gpIV antibody
see all
图片
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Lane 1 : Anti-Varicella Zoster Virus gI antibody [8C4] (ab52552) at 1/100 dilution
Lane 2 : Anti-Varicella Zoster Virus gI antibody [8C4] (ab52552) at 1/200 dilution
Lane 3 : Anti-Varicella Zoster Virus gI antibody [8C4] (ab52552) at 1/400 dilution
Lane 4 : Anti-Varicella Zoster Virus gI antibody [8C4] (ab52552) at 1/800 dilution
All lanes : VZV Infected Cell Extract at 50 µg/cm
Predicted band size: 39 kDa
Observed band size: 55 kDa why is the actual band size different from the predicted? -
VZV slides (human fibroblast) labelled with ab52552 at 1/1600 followed by anti-Mouse-FITC F(ab')2 with counterstain
实验方案
数据表及文件
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Datasheet download
文献 (1)
ab52552 被引用在 1 文献中.
- Wang W et al. Development of a skin- and neuro-attenuated live vaccine for varicella. Nat Commun 13:824 (2022). PubMed: 35149692