Anti-VAP1抗体[174-5] (ab81718)
![Immunohistochemistry (Frozen sections) - Anti-VAP1 antibody [174-5] (ab81718)](https://www.abcam.cn/ps/products/81/ab81718/Images/ab81718-96857-anti-vap1-antibody-174-5-immunohistochemistry.gif "Immunohistochemistry (Frozen sections) - Anti-VAP1 antibody [174-5] (ab81718)")
Key features and details
- Mouse monoclonal [174-5] to VAP1
- Suitable for: IHC-Fr
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-VAP1抗体[174-5]
参阅全部 VAP1 一抗 -
描述
小鼠单克隆抗体[174-5] to VAP1 -
宿主
Mouse -
经测试应用
适用于: IHC-Frmore details -
种属反应性
与反应: Human -
免疫原
Tissue, cells or virus corresponding to Human VAP1.
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阳性对照
- Human tonsil tissue.
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常规说明
This antibody inhibits lymphocyte infiltration in liver allograft rejection in rats.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Constituents: 0.1% BSA, PBS -
Concentration information loading... -
纯化说明
ab81718 is purified and 0.2µM filtered. -
Primary antibody说明
This antibody inhibits lymphocyte infiltration in liver allograft rejection in rats. -
克隆
单克隆 -
克隆编号
174-5 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab81718于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-Fr |
1/50.
|
| 说明 |
|---|
|
IHC-Fr
1/50. |
靶标
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功能
Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis. -
组织特异性
Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis. -
序列相似性
Belongs to the copper/topaquinone oxidase family. -
翻译后修饰
Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
N- and O-glycosylated. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 8639 Human
- Omim: 603735 Human
- SwissProt: Q16853 Human
- Unigene: 198241 Human
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别名
- Amine oxidase, copper containing 3 (vascular adhesion protein 1) antibody
- AOC3 antibody
- AOC3_HUMAN antibody
see all
图片
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Immunohistochemistry (Frozen sections) - Anti-VAP1 antibody [174-5] (ab81718)
ab81718 at 1/50 dilution staining VAP1 in human tonsil tissue section by Immunohistochemistry (frozen sections).
数据表及文件
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Datasheet download
文献 (2)
ab81718 被引用在 2 文献中.
- Zhang Y et al. Hypoxia serves a key function in the upregulated expression of vascular adhesion protein-1 in vitro and in a rat model of hemorrhagic shock. Mol Med Rep 16:1189-1199 (2017). PubMed: 28627649
- Martelius T et al. Blockade of vascular adhesion protein-1 inhibits lymphocyte infiltration in rat liver allograft rejection. Am J Pathol 165:1993-2001 (2004). PubMed: 15579442
