Anti-Uteroglobin抗体(ab40873)
Key features and details
- Rabbit polyclonal to Uteroglobin
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
-
产品名称
Anti-Uteroglobin抗体
参阅全部 Uteroglobin 一抗 -
描述
兔多克隆抗体to Uteroglobin -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Mouse -
免疫原
Recombinant rat uteroglobin His fusion protein.
-
常规说明
This antibody is useful for distinguishing ciliated from non-ciliated cells in the adult mouse lung.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.01% Sodium azide
Constituent: Whole serum -
Concentration information loading... -
纯度
Whole antiserum -
Primary antibody说明
This antibody is useful for distinguishing ciliated from non-ciliated cells in the adult mouse lung. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab40873于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P | (3) |
1/1600.
|
| 说明 |
|---|
|
IHC-P
1/1600. |
靶标
-
功能
Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. -
组织特异性
Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways). -
序列相似性
Belongs to the secretoglobin family. -
细胞定位
Secreted. - Information by UniProt
-
数据库链接
- Entrez Gene: 22287 Mouse
- SwissProt: Q06318 Mouse
- Unigene: 2258 Mouse
-
别名
- Blastokinin antibody
- CC10 antibody
- CC16 antibody
see all
图片
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Uteroglobin antibody (ab40873)
Adult mouse lung was embedded in paraffin and stained with ab40873 (1:1600 dilution).
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Uteroglobin antibody (ab40873)Image courtesy of an anonymous Abreview.ab40873 staining Uteroglobin in human lung parenchyma tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Tissue was fixed with formaldehyde and a heat mediated antigen retrieval step was performed using 10mM citrate buffer. Samples were then blocked with 1% BSA, 0.1% Triton-X/ PBS for 15 minutes at 18°C followed by incubation with the primary antibody at a 1/500 dilution for 16 hours at 4°C. An HRP-conjugated pig anti-rabbit polyclonal was used as secondary antibody at a 1/100 dilution.
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (37)
ab40873 被引用在 37 文献中.
- Munis AM et al. A human surfactant B deficiency air-liquid interface cell culture model suitable for gene therapy applications. Mol Ther Methods Clin Dev 20:237-246 (2021). PubMed: 33426150
- Liu Y et al. Proteomic Analysis Revealed the Characteristics of Key Proteins Involved in the Regulation of Inflammatory Response, Leukocyte Transendothelial Migration, Phagocytosis, and Immune Process during Early Lung Blast Injury. Oxid Med Cell Longev 2021:8899274 (2021). PubMed: 34007409
- Bentley-Ford MR et al. A mouse model of BBS identifies developmental and homeostatic effects of BBS5 mutation and identifies novel pituitary abnormalities. Hum Mol Genet 30:234-246 (2021). PubMed: 33560420
- Lee H et al. mTORC1 is a mechanosensor that regulates surfactant function and lung compliance during ventilator-induced lung injury. JCI Insight 6:N/A (2021). PubMed: 34138757
- Rosigkeit S et al. Definitive evidence for Club cells as progenitors for mutant Kras/Trp53-deficient lung cancer. Int J Cancer 149:1670-1682 (2021). PubMed: 34331774