Anti-USP35抗体

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

USP35 plays a role in regulating protein stability and turnover. As part of deubiquitinating enzymes (DUBs) it helps reverse the ubiquitination process that marks proteins for degradation. It contributes to maintaining protein homeostasis which is important for cell function and survival. USP35 may function as part of larger protein complexes although specific complexes have not been definitively described. Its regulatory role can impact cellular processes significantly.

Pathways

The ubiquitin-proteasome pathway involves USP35 in maintaining protein balance by removing ubiquitin chains. USP35 interacts with other DUBs as well as the proteasome system itself. It is also associated with the ER-associated degradation (ERAD) pathway which controls protein quality in the endoplasmic reticulum. USP35 interacts closely with proteins like HRD1 which is another E3 ubiquitin ligase involved in ERAD highlighting the interconnected nature of protein regulation pathways.