Anti-USP15抗体(ab4850)
Key features and details
- Goat polyclonal to USP15
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-USP15抗体
参阅全部 USP15 一抗 -
描述
山羊多克隆抗体to USP15 -
宿主
Goat -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Rat, Cow, Dog, Pig
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免疫原
Synthetic peptide corresponding to Human USP15 aa 970-981 (C terminal).
Sequence:NDIENENCMHTN
Database link: Q9Y4E8 -
常规说明
Gene Ontology terms - ubiquitin-specific protease activity; cysteine-type endopeptidase activity; deubiquitination.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 2.5 - 3.8 µg/ml.
Perform heat mediated antigen retrieval with citrate buffer (pH6). |
| 说明 |
|---|
|
IHC-P
Use a concentration of 2.5 - 3.8 µg/ml. Perform heat mediated antigen retrieval with citrate buffer (pH6). |
靶标
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功能
Protease that degrades 'Lys-48'-linked polyubiquitin chains. Protects target proteins against proteasomal degradation. Protects APC and human papillomavirus type 16 protein E6 against degradation via the ubiquitin proteasome pathway. -
组织特异性
Expressed in skeletal muscle, kidney, heart, placenta, liver, thymus, lung, and ovary, with little or no expression in other tissues. -
序列相似性
Belongs to the peptidase C19 family.
Contains 1 DUSP domain. -
翻译后修饰
Phosphorylated. Phosphorylation protects against ubiquitination and subsequent degradation by the proteasome.
Ubiquitinated, leading to degradation by the proteasome. - Information by UniProt
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数据库链接
- Entrez Gene: 538284 Cow
- Entrez Gene: 9958 Human
- Entrez Gene: 171329 Rat
- Omim: 604731 Human
- SwissProt: Q9Y4E8 Human
- Unigene: 434951 Human
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别名
- Deubiquitinating enzyme 15 antibody
- Deubiquitinating enzyme antibody
- EC 3 1 2 15 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-USP15 antibody (ab4850)
Immunohistochemical analysis of paraffin embedded Human Liver labeling USP15 with ab4850 at 2.5-3.8µg/ml. The image shows patterned intracellular staining in hepatocytes.
Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
数据表及文件
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Datasheet download
文献 (1)
ab4850 被引用在 1 文献中.
- Zhao Y et al. USP15 Enhances Re-epithelialization Through Deubiquitinating EIF4A1 During Cutaneous Wound Repair. Front Cell Dev Biol 8:529 (2020). PubMed: 32671073
