Anti-Ugt2b抗体(ab113433)
Key features and details
- Goat polyclonal to Ugt2b
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-Ugt2b抗体 -
描述
山羊多克隆抗体to Ugt2b -
宿主
Goat -
特异性
ab113433 is not expected to cross-react with other Ugt2 proteins. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat -
免疫原
Synthetic peptide:
KLDFLSALEEVIDN
by a Cysteine residue linker, corresponding to internal sequence amino acids 423-436 of Rat Ugt2b (NP_113721.3). -
阳性对照
- Rat Kidney lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
纯化说明
ab113433 was purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab113433于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 61 kDa). Primary incubation time: 1 hour.
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| 说明 |
|---|
|
WB
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 61 kDa). Primary incubation time: 1 hour. |
靶标
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相关性
Ugt2b is an enzyme involved in conjugating lipophilic aglycon substrates with glucuronic acid [RGD]. Ugt2b is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds acting on various endogenous steroids, especially etiocholanolone and androsterone. -
细胞定位
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. -
数据库链接
- Entrez Gene: 24862 Rat
- SwissProt: P08541 Rat
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别名
- 3 hydroxyandrogen specific UDPGT antibody
- Androsterone UDP glucuronosyltransferase antibody
- RLUG 23 antibody
see all
图片
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Western blot - Anti-Ugt2b antibody (ab113433)Anti-Ugt2b antibody (ab113433) at 0.1 µg/ml + Rat Kidney lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 61 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab113433 被引用在 2 文献中.
- Hao Z et al. The inhibition of tamoxifen on UGT2B gene expression and enzyme activity in rat liver contribute to the estrogen homeostasis dysregulation. BMC Pharmacol Toxicol 23:33 (2022). PubMed: 35642027
- Wan X et al. Histomorphological and ultrastructural cadmium-induced kidney injuries and precancerous lesions in rats and screening for biomarkers. Biosci Rep 42:N/A (2022). PubMed: 35678542