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重组RabMAb

重组Anti-UCKL1抗体[EPR7384] (ab126754)

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Western blot - Anti-UCKL1 antibody [EPR7384] (ab126754)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-UCKL1 antibody [EPR7384] (ab126754)
  • OI-RD Scanning - Anti-UCKL1 antibody [EPR7384] (ab126754)
  • Anti-UCKL1 antibody [EPR7384] (ab126754)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR7384] to UCKL1
  • Suitable for: WB, IHC-P
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Carrier Free

概述

  • 产品名称

    Anti-UCKL1抗体[EPR7384]
    参阅全部 UCKL1 一抗

  • 描述

    兔单克隆抗体[EPR7384] to UCKL1

  • 宿主

    Rabbit

  • 经测试应用

    适用于: WB, IHC-Pmore details
    不适用于: Flow Cyt,ICC/IF or IP

  • 种属反应性

    与反应: Human
    预测可用于: Mouse

  • 免疫原

    Synthetic peptide within Human UCKL1 aa 500-600. The exact sequence is proprietary.

  • 阳性对照

    • 293T and HeLa cell lysates; Human kidney tissue.

  • 常规说明

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

性能

  • 形式

    Liquid

  • 存放说明

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

  • 解离常数（KD）

    KD = 5.30 x 10 -11 M
    Learn more about KD

  • 存储溶液

    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant
  • Concentration information loading...

  • 纯度

    Protein A purified

  • 克隆

    单克隆

  • 克隆编号

    EPR7384

  • 同种型

    IgG

  • 研究领域

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab126754于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
WB
1/1000 - 1/10000. Predicted molecular weight: 61 kDa.
IHC-P
1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
说明
WB
1/1000 - 1/10000. Predicted molecular weight: 61 kDa.
IHC-P
1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
应用说明
Is unsuitable for Flow Cyt,ICC/IF or IP.

靶标

  • 功能

    May contribute to UTP accumulation needed for blast transformation and proliferation.

  • 组织特异性

    Ubiquitous.

  • 通路

    Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.
    Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.

  • 序列相似性

    Belongs to the uridine kinase family.

  • 翻译后修饰

    Ubiquitinated by RNF19B; which induces proteasomal degradation.

  • 细胞定位

    Cytoplasm. Nucleus. EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.
  • Information by UniProt

  • 数据库链接

    • 别名

      • F538 antibody
      • UCK 1L antibody
      • UCK1 like antibody
      • UCK1L antibody
      • UCKL 1 antibody
      • UCKL1 antibody
      • UCKL1_HUMAN antibody
      • Uridine cytidine kinase 1 like 1 antibody
      • Uridine kinase like 1 antibody
      • Uridine-cytidine kinase-like 1 antibody
      • Uridine/cytidine kinase like 1 antibody
      • URKL 1 antibody
      • URKL1 antibody
      see all

    图片

    • Western blot - Anti-UCKL1 antibody [EPR7384] (ab126754)
      Western blot - Anti-UCKL1 antibody [EPR7384] (ab126754)
      All lanes : Anti-UCKL1 antibody [EPR7384] (ab126754) at 1/1000 dilution

      Lane 1 : 293T (Human embryonic kidney epithelial cell) cell lysate
      Lane 2 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP-conjugated goat anti-rabbit at 1/2000 dilution

      Predicted band size: 61 kDa

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-UCKL1 antibody [EPR7384] (ab126754)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-UCKL1 antibody [EPR7384] (ab126754)

      ab126754, at 1/100 dilution, staining UCKL1 in paraffin-embedded Human kidney tissue by Immunohistochemistry.

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    • OI-RD Scanning - Anti-UCKL1 antibody [EPR7384] (ab126754)
      OI-RD Scanning - Anti-UCKL1 antibody [EPR7384] (ab126754)
      Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD
    • Anti-UCKL1 antibody [EPR7384] (ab126754)
      Anti-UCKL1 antibody [EPR7384] (ab126754)

    文献 (0)

    发表研究结果有使用 ab126754？请让我们知道，以便我们可以引用本数据表中的参考文章。

    ab126754 尚未被引用在任何文献中。

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