Anti-TTC37抗体(ab122421)
Key features and details
- Rabbit polyclonal to TTC37
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TTC37抗体
参阅全部 TTC37 一抗 -
描述
兔多克隆抗体to TTC37 -
宿主
Rabbit -
经测试应用
适用于: ICC/IF, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
antigen sequence: QLGLTYWFMG EETRKDKTKA LTHFLKAARL DTYMGKVFCY LGHYYRDVVG DKNRARGCYR KAFELDDTDA ESGAAAVDLS VELEDMEMAL AILTTVTQK, corresponding to amino acids 459-557 of Human TTC37.
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阳性对照
- Human stomach tissue
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab122421于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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| IHC-P |
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 说明 |
|---|
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ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
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IHC-P
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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组织特异性
Widely expressed with the highest levels observed in vascular tissues, lymph node, pituitary, lung and intestine. Not expressed in the liver. -
疾病相关
Note=Defects in TTC37 are associated with Trico-Hepato-Enteric syndrome (THE). THE syndrome is a rare and severe autosonmal recessive condition that associates intractable diarrhea with facial dysmorphism, intrauterine growth retardation immunodeficiency with low serum concentrations of immunoglobulins and hair abnormalities characterized by woolly hair. -
序列相似性
Contains 20 TPR repeats. - Information by UniProt
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数据库链接
- Entrez Gene: 9652 Human
- SwissProt: Q6PGP7 Human
- Unigene: 482868 Human
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别名
- KIAA0372 antibody
- Tetratricopeptide repeat protein 37 antibody
- Thespin antibody
see all
图片
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Immunocytochemistry/ Immunofluorescence - Anti-TTC37 antibody (ab122421)Immunofluorescent staining of Human cell line A-431 shows positivity in nucleus but not nucleoli and cytoplasm. Recommended concentration of ab122421 1-4 µg/ml. Cells treated with PFA/Triton X-100.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TTC37 antibody (ab122421)ab122421 at 1/35 dilution staining TTC37 in Paraffin-embedded Human stomach tissue by Immunohistochemistry.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab122421 被引用在 1 文献中.
- Eckard SC et al. The SKIV2L RNA exosome limits activation of the RIG-I-like receptors. Nat Immunol 15:839-45 (2014). PubMed: 25064072