Anti-TRPC3抗体(ab51560)
Key features and details
- Rabbit polyclonal to TRPC3
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-TRPC3抗体
参阅全部 TRPC3 一抗 -
描述
兔多克隆抗体to TRPC3 -
宿主
Rabbit -
特异性
ab51560 can be used for the detection of TRPC3. -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Synthetic peptide within Human TRPC3 aa 100-200 (N terminal). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. Corresponding to 14 amino acids near to the N terminal of Human TRPC3.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab51560于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (1) |
Use at an assay dependent concentration.
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| IHC-P | (1) |
Use a concentration of 10 µg/ml.
|
| 说明 |
|---|
|
WB
Use at an assay dependent concentration. |
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IHC-P
Use a concentration of 10 µg/ml. |
靶标
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相关性
TRPC channels form the subfamily of channels in human most closely related to drosophila TRP channels. Structurally, this family shares a number of similar characteristics. At the proximal C-terminus of this sub-family is a TRP box motif containing the invariant EWKFAR sequence and between 3 and 4 ankyrin repeats near the N-terminus. These channels are non-selectively permeable to cations, with a selectivity of calcium over sodium variable among the different members. Many of TRPC channel subunits are able to coassemble. -
细胞定位
Cell Membrane; multi-pass membrane protein -
数据库链接
- Entrez Gene: 7222 Human
- Entrez Gene: 22065 Mouse
- Omim: 602345 Human
- SwissProt: Q13507 Human
- SwissProt: Q9QZC1 Mouse
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别名
- Htrp 3 antibody
- Htrp3 antibody
- MGC124333 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRPC3 antibody (ab51560)Immunohistochemistry of TRPC3 in mouse heart tissue with TRPC3 antibody ab51560 at 10 µg/ml.
数据表及文件
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SDS download
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Datasheet download
文献 (17)
ab51560 被引用在 17 文献中.
- Chen J et al. MiRNA-26a-5p inhibits preterm labor initiation by targeting and regulating TRPC3 ion channel protein expression. Environ Toxicol 39:357-366 (2024). PubMed: 37755144
- Lee TW et al. Fibroblast Growth Factor 23 Stimulates Cardiac Fibroblast Activity through Phospholipase C-Mediated Calcium Signaling. Int J Mol Sci 23:N/A (2021). PubMed: 35008591
- Chen PH et al. Lithium Reduces Migration and Collagen Synthesis Activity in Human Cardiac Fibroblasts by Inhibiting Store-Operated Ca2+ Entry. Int J Mol Sci 22:N/A (2021). PubMed: 33467715
- Rafael Lopez J et al. Transient Receptor Potential Cation Channels and Calcium Dyshomeostasis in a Mouse Model Relevant to Malignant Hyperthermia. Anesthesiology 133:364-376 (2020). PubMed: 32665491
- Fletcher NF et al. A novel antiviral formulation inhibits a range of enveloped viruses. J Gen Virol 101:1090-1102 (2020). PubMed: 32692647