Anti-TRPC1抗体(ab110837)
Key features and details
- Goat polyclonal to TRPC1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TRPC1抗体
参阅全部 TRPC1 一抗 -
描述
山羊多克隆抗体to TRPC1 -
宿主
Goat -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Dog
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免疫原
Synthetic peptide to an internal region of Human TRPC1 conjugated to KLH.
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阳性对照
- Human cortex, Human Prostate (fibromuscular stroma)
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab110837于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 说明 |
|---|
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IHC-P
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. -
组织特异性
Seems to be ubiquitous. -
序列相似性
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
Contains 4 ANK repeats. -
翻译后修饰
Activation of PRKCA induces phosphorylation of TRPC1 and subsequent Ca2+ entry into cells. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 7220 Human
- Entrez Gene: 22063 Mouse
- Entrez Gene: 89821 Rat
- Omim: 602343 Human
- SwissProt: P48995 Human
- SwissProt: Q61056 Mouse
- SwissProt: Q9QX01 Rat
- Unigene: 250687 Human
see all -
别名
- HTRP 1 antibody
- HTRP1 antibody
- MGC133334 antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRPC1 antibody (ab110837)ab110837 at 3.75 µg/ml staining TRPC1 in Human cortex by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRPC1 antibody (ab110837)ab110837 at 3.75 µg/ml staining TRPC1 in Human Prostate (fibromuscular stroma) by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab110837 被引用在 1 文献中.
- Zeng YZ et al. TRPC1 Inhibits Cell Proliferation/Invasion and Is Predictive of a Better Prognosis of Esophageal Squamous Cell Carcinoma. Front Oncol 11:627713 (2021). PubMed: 33854967