Anti-TRH-R抗体(ab72179)
Key features and details
- Rabbit polyclonal to TRH-R
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TRH-R抗体 -
描述
兔多克隆抗体to TRH-R -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Opossum
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免疫原
Synthetic peptide corresponding to Human TRH-R aa 350-400 (C terminal).
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阳性对照
- Human brain lysate. Human thyroid tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 0.2% Gelatin, PBS -
Concentration information loading... -
纯度
Protein G purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab72179于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).
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| IHC-P |
Use a concentration of 10 µg/ml.
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| 说明 |
|---|
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WB
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa). |
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IHC-P
Use a concentration of 10 µg/ml. |
靶标
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功能
Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 281549 Cow
- Entrez Gene: 7201 Human
- Entrez Gene: 22045 Mouse
- Entrez Gene: 25570 Rat
- Omim: 188545 Human
- SwissProt: O46639 Cow
- SwissProt: P34981 Human
- SwissProt: P21761 Mouse
see all -
别名
- Thyroliberin receptor antibody
- Thyrotropin Releasing Hormone Receptor antibody
- Thyrotropin-releasing hormone receptor antibody
see all
图片
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Western blot - Anti-TRH-R antibody (ab72179)All lanes : Anti-TRH-R antibody (ab72179) at 0.5 µg/ml
Lane 1 : Human brain lysate
Lane 2 : Human brain lysate with immunising peptide
Predicted band size: 45 kDa
Observed band size: 45 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRH-R antibody (ab72179)ab72179 at 10µg/ml staining TRH-R in human thyroid by Immunohistochemistry using paraffin-embedded tissue.
数据表及文件
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Datasheet download
文献 (4)
ab72179 被引用在 4 文献中.
- Pech-Pool S et al. Thyrotropin-Releasing Hormone (TRH) and Somatostatin (SST), but not Growth Hormone-Releasing Hormone (GHRH) nor Ghrelin (GHRL), Regulate Expression and Release of Immune Growth Hormone (GH) from Chicken Bursal B-Lymphocyte Cultures. Int J Mol Sci 21:N/A (2020). PubMed: 32093298
- Pijnacker T et al. TRH-induced secretion of adrenocorticotropin and cortisol in dogs with pituitary-dependent hypercortisolism. Vet Q 38:72-78 (2018). PubMed: 30362899
- Zhang Y et al. The potential role of thyrotropin-releasing hormone in colonic dysmotility induced by water avoidance stress in rats. Neuropeptides N/A:N/A (2018). WB, IHC-P . PubMed: 29803395
- Puissant MM et al. RNASeq-derived transcriptome comparisons reveal neuromodulatory deficiency in the CO2 insensitive brown Norway rat. J Physiol 593:415-30 (2015). PubMed: 25630262
