AB217293

Anti-Trehalase抗体

Name: Trehalase抗体 (ab217293)| Abcam中文官网
Brand: Abcam Limited
SKU: AB217293
Price: 4845 CNY
Availability: InStock

Anti-Trehalase antibody

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(1 Publication)

Rabbit Polyclonal Trehalase antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human TREH aa 50-150 conjugated to Keyhole Limpet Haemocyanin.

查看别名

TREA, TREH, Trehalase

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Trehalase antibody (AB217293)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Trehalase antibody (AB217293)

Immunohistochemical analysis of formalin-fixed paraffin-embedded sections of human kidney tissue labeling Trehalase with ab217293 at a 1/200 dilution, followed by conjugation to a secondary antibody and DAB staining.

Supplier Data

Western blot - Anti-Trehalase antibody (AB217293)

All lanes:

Western blot - Anti-Trehalase antibody (ab217293) at 1/500 dilution

All lanes:

mouse stomach lysate

Secondary

All lanes:

HRP conjugated goat anti-rabbit IgG (H+L) at 1/5000 dilution

Predicted band size: 67 kDa

false

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human, Mouse

应用

IHC-P, WB

applications

免疫原

Synthetic Peptide within Human TREH aa 50-150 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

O43280

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Trehalase also known as TREH is an enzyme responsible for the hydrolysis of trehalose into two glucose molecules. It has a molecular mass of approximately 65 kDa. This enzyme is mainly expressed in the small intestine brush border membrane and kidney. The presence of trehalase in these regions of the body suggests it plays an important role in carbohydrate digestion.

Biological function summary

Trehalase facilitates the conversion of trehalose a non-reducing disaccharide which serves as an important energy source for various organisms. By breaking down trehalose the enzyme contributes to glucose homeostasis within the body. Trehalase does not form part of any known multi-protein complexes functioning as an independent enzyme in cellular metabolism.

Pathways

Trehalase participates in the carbohydrate digestion and absorption pathway. This pathway involves converting dietary carbohydrates into simple sugars that the body can utilize for energy. Trehalase operates in conjunction with other enzymes like lactase and sucrase-isomaltase that also contribute to carbohydrate digestion within the gastrointestinal tract.

Trehalase deficiency can lead to digestive issues notably trehalose intolerance where affected individuals experience symptoms after consuming foods containing trehalose. Additionally trehalase activity has connections to diabetes as it directly influences glucose levels and metabolism. Adjustments in trehalase activity may affect the concentration of glucose in the bloodstream impacting individuals with diabetes by potentially altering their glucose homeostasis.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.

See full target information TREH

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of cell communication and signaling 16:579-599 PubMed35581421

2022

Lysine demethylase 5A promotes prostate adenocarcinoma progression by suppressing microRNA-330-3p expression and activating the COPB2/PI3K/AKT axis in an ETS1-dependent manner.

Applications

Unspecified application

Species

Unspecified reactive species

Yuanyuan Mi,Lifeng Zhang,Chuanyu Sun,Yanyan Feng,Jian Sun,Jun Wang,Dongjie Yang,Xiaowei Qi,Hongyuan Wan,Guowei Xia,Sheng Wu,Lijie Zhu

View all publications

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Anti-Trehalase抗体

Anti-Trehalase antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Trehalase antibody (AB217293)

Western blot - Anti-Trehalase antibody (AB217293)