Anti-TRAF6BP/TAX1BP1抗体(ab121812)
Key features and details
- Rabbit polyclonal to TRAF6BP/TAX1BP1
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-TRAF6BP/TAX1BP1抗体
参阅全部 TRAF6BP/TAX1BP1 一抗 -
描述
兔多克隆抗体to TRAF6BP/TAX1BP1 -
宿主
Rabbit -
经测试应用
适用于: ICC/IF, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment corresponding to Human TRAF6BP/TAX1BP1 aa 406-540.
Database link: Q86VP1 -
阳性对照
- IHC-P: Human testis, prostate and placenta tissue ICC/IF: U-2 OS cells
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab121812于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
|
|
IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
说明 |
---|
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
-
功能
Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. -
组织特异性
Expressed in all tissues tested. - Information by UniProt
-
数据库链接
- Entrez Gene: 8887 Human
- Omim: 605326 Human
- SwissProt: Q86VP1 Human
- Unigene: 34576 Human
-
别名
- 1200003J11Rik antibody
- 1700069J21Rik antibody
- Aa1076 antibody
see all
图片
-
Immunofluorescent staining of Human cell line U-2 OS shows positivity in cytoplasm. Recommended concentration of ab121812 1-4 µg/ml. Cells treated with PFA/Triton X-100.
-
Immunohistochemical analysis of human testis tissue labeling TRAF6BP/TAX1BP1 with ab121812 at 1/50 dilution.
-
Immunohistochemical analysis of human prostate tissue labeling TRAF6BP/TAX1BP1 with ab121812 at 1/50 dilution.
-
Immunohistochemical analysis of human placenta tissue labeling TRAF6BP/TAX1BP1 with ab121812 at 1/50 dilution.
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab121812 被引用在 1 文献中.
- Hernandez D et al. Interferon-Inducible E3 Ligase RNF213 Facilitates Host-Protective Linear and K63-Linked Ubiquitylation of Toxoplasma gondii Parasitophorous Vacuoles. mBio 13:e0188822 (2022). PubMed: 36154443