AB89624

Anti-TOM70抗体

Name: TOM70抗体 (ab89624)| Abcam中文官网
Brand: Abcam Limited
SKU: AB89624
Price: 4990 CNY
Availability: InStock
Rating: 5 (1 reviews)

Anti-TOM70 antibody

(1 Review)

(6 Publications)

Mouse Polyclonal TOM70 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human TOMM70.

查看别名

KIAA0719, TOM70, TOMM70A, TOMM70, Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor, Translocase of outer membrane 70 kDa subunit, Translocase of outer mitochondrial membrane protein 70

1 Images

Unknown

Western blot - Anti-TOM70 antibody (AB89624)

All lanes:

Western blot - Anti-TOM70 antibody (ab89624) at 1 µg/mL

All lanes:

human liver tissue lysate at 50 µg

Predicted band size: 67 kDa

Observed band size: 67 kDa

false

关键信息

宿主种属

Mouse

克隆

Polyclonal

亚型

IgG

不含载体蛋白

Yes

反应种属

Human

应用

applications

免疫原

Recombinant Full Length Protein corresponding to Human TOMM70.

O94826

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Protein A

存储溶液

pH: 7.4 Constituents: PBS

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

Acts as a receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) (PubMed : 12526792). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (PubMed : 12526792, PubMed : 35025629). Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection (PubMed : 20628368, PubMed : 25609812, PubMed : 32728199). Upon Sendai virus infection, recruits HSP90AA1 : IRF3 : BAX in mitochondrion and the complex induces apoptosis (PubMed : 25609812).

See full target information TOMM70

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文献 (6)

Recent publications for all applications. Explore the full list and refine your search

Endocrinology 164: PubMed37586092

2023

Luteal Lipid Droplets: A Novel Platform for Steroid Synthesis.

Applications

Unspecified application

Species

Unspecified reactive species

Michele R Plewes,Heather A Talbott,Anthony J Saviola,Nicholas T Woods,Micah B Schott,John S Davis

Frontiers in aging neuroscience 14:1013943 PubMed36408108

2022

Impact prediction of translocation of the mitochondrial outer membrane 70 as biomarker in Alzheimer's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Xi Cao,Yanting Chen,Xiaoyu Sang,Shunliang Xu,Zhaohong Xie,Zhengyu Zhu,Ping Wang,Jianzhong Bi,Linlin Xu

Frontiers in cell and developmental biology 8:617762 PubMed33537307

2021

Interplay Between Mitophagy and Apoptosis Defines a Cell Fate Upon Co-treatment of Breast Cancer Cells With a Recombinant Fragment of Human κ-Casein and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand.

Applications

Unspecified application

Species

Unspecified reactive species

Fabian Wohlfromm,Max Richter,Lado Otrin,Kamil Seyrek,Tanja Vidaković-Koch,Elena Kuligina,Vladimir Richter,Olga Koval,Inna N Lavrik

PLoS genetics 16:e1008923 PubMed32735630

2020

RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases.

Applications

Unspecified application

Species

Unspecified reactive species

Aurelio Reyes,Paola Favia,Sara Vidoni,Vittoria Petruzzella,Massimo Zeviani

Cancers 12: PubMed32486420

2020

The Recombinant Fragment of Human κ-Casein Induces Cell Death by Targeting the Proteins of Mitochondrial Import in Breast Cancer Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Max Richter,Fabian Wohlfromm,Thilo Kähne,Hannes Bongartz,Kamil Seyrek,Yuriy Kit,Olga Chinak,Vladimir A Richter,Olga A Koval,Inna N Lavrik

The Journal of biological chemistry 288:2223-37 PubMed23212910

2012

Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons.

Applications

Species

Human

Aleksandar Rakovic,Katharina Shurkewitsch,Philip Seibler,Anne Grünewald,Alessandra Zanon,Johann Hagenah,Dimitri Krainc,Christine Klein

View all publications

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Abcam Product Promise

我们致力于为您的研究提供高质量的试剂，为您科研的每一步提供支持。若我们的产品未能达到预期性能，我们向您提供 Abcam Product Promise 保障。

详情请参阅我们的条款与条件。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-TOM70抗体

Anti-TOM70 antibody

Western blot - Anti-TOM70 antibody (AB89624)

关键信息

宿主种属

克隆

亚型

不含载体蛋白

反应种属

应用

免疫原

反应性数据

性能和储存信息

形式

纯化工艺

存储溶液

运输条件

推荐的短期储存条件

推荐的长期储存条件

分装信息

储存信息

产品实验方案

靶点信息

文献 (6)

Abcam Product Promise

Anti-TOM70抗体

Anti-TOM70 antibody

Western blot - Anti-TOM70 antibody (AB89624)

关键信息

宿主种属

克隆

亚型

不含载体蛋白

反应种属

应用

免疫原

替代产品

Primary Antibodies

搭配使用产品

Assay Kits

Primary Antibodies

Primary Antibodies

Reagents, Controls & Accessories

Primary Antibodies

反应性数据

性能和储存信息

形式

纯化工艺

存储溶液

运输条件

推荐的短期储存条件

推荐的长期储存条件

分装信息

储存信息

产品实验方案

靶点信息

文献 (6)

Abcam Product Promise