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AB122598

Anti-TMEM72抗体

Anti-TMEM72 antibody

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(1 Publication)

Rabbit Polyclonal TMEM72 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TMEM72 aa 100-200.

查看别名

C10orf127, KSP37, TMEM72, Transmembrane protein 72, Kidney-specific secretory protein of 37 kDa

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM72 antibody (AB122598)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM72 antibody (AB122598)

ab122598, at 1/200 dilution, staining TMEM72 in paraffin embedded Human kidney tissue by Immunohistochemistry.

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

IHC-P

applications

免疫原

Recombinant Fragment Protein within Human TMEM72 aa 100-200. The exact immunogen used to generate this antibody is proprietary information.

A0PK05

反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." } } }

性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
存储溶液
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
运输条件
Blue Ice
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
储存信息
Avoid freeze / thaw cycle|Store undiluted

补充信息

This supplementary information is collated from multiple sources and compiled automatically.

TMEM72 also known as Transmembrane Protein 72 is a transmembrane protein with a mass of approximately 23 kDa. TMEM72 exhibits expression in various tissues including the kidney and liver. It primarily locates in the membrane structure where it participates in cellular transport processes. The protein possesses domains that facilitate interactions with other cellular components contributing to its mechanical functions.
Biological function summary

TMEM72 involves itself in cellular homeostasis and regulatory processes. It operates as part of cellular transport systems influencing ion balance within cells. TMEM72 does not function alone and is part of the larger complex of proteins that regulate membrane permeability. Its activity impacts how cells respond to environmental changes which affects the overall functioning of organ systems where it is expressed.

Pathways

Researchers link TMEM72 to significant cellular pathways such as ion transport and homeostasis. In these pathways it interacts with other proteins including ion channel proteins to manage ion flow across membranes. TMEM72 plays a role in maintaining the electrochemical gradients necessary for cell survival and proper function positioning it as an important component in both the physiological and pathophysiological contexts.

TMEM72 may relate to conditions affecting ion balance and membrane transport. Abnormalities in this protein's function can be observed in certain kidney diseases where ion transport is disrupted. Additionally TMEM72 might have connections to liver disorders in which impaired regulation of ion flow exacerbates disease progression. Proteins such as ion channels associate with these diseases with TMEM72 acting as an important to understanding and potentially targeting these disorders for therapeutic interventions.

产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 15:3793 PubMed38714822

2024

An interphase actin wave promotes mitochondrial content mixing and organelle homeostasis.

Applications

Unspecified application

Species

Unspecified reactive species

Stephen M Coscia,Andrew S Moore,Cameron P Thompson,Christian F Tirrito,E Michael Ostap,Erika L F Holzbaur
View all publications

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