Anti-TMEM59抗体(ab105417)
Key features and details
- Rabbit polyclonal to TMEM59
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TMEM59抗体
参阅全部 TMEM59 一抗 -
描述
兔多克隆抗体to TMEM59 -
宿主
Rabbit -
特异性
Multiple isoforms of TMEM59 are known to exist. This antibody is predicted to not cross-react with other TMEM family members. -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
A 16 amino acid peptide near amino terminus of Human TMEM59 (NP_004863)
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阳性对照
- Human Kidney Tissue Lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab105417于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IF |
Use a concentration of 20 µg/ml.
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| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 36 kDa.
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| IHC-P |
Use a concentration of 2.5 µg/ml.
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| 说明 |
|---|
|
IF
Use a concentration of 20 µg/ml. |
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 36 kDa. |
|
IHC-P
Use a concentration of 2.5 µg/ml. |
靶标
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功能
Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding. -
序列相似性
Belongs to the TMEM59 family. -
翻译后修饰
N-glycosylated. -
细胞定位
Golgi apparatus membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 9528 Human
- SwissProt: Q9BXS4 Human
- Unigene: 726034 Human
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别名
- C1orf8 antibody
- HSPC001 antibody
- Liver membrane-bound protein antibody
see all
图片
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Western blot - Anti-TMEM59 antibody (ab105417)All lanes : Anti-TMEM59 antibody (ab105417) at 1 µg/ml
Lane 1 : Human kidney tissue lysate
Lane 2 : Human kidney tissue lysate with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 36 kDa -
Immunofluorescence - Anti-TMEM59 antibody (ab105417)Immunofluorescence of TMEM59 in Human kidney tissue with ab105417 at 20 ug/mL. -
Immunohistochemistry paraffin embedded sections - Anti-TMEM59 antibody (ab105417)Immunohistochemistry of TMEM59 in human kidney tissue with ab105417 at 2.5 µg/ml.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab105417 被引用在 1 文献中.
- Yang H et al. An Analysis of the Gene Expression Associated with Lymph Node Metastasis in Colorectal Cancer. Int J Genomics 2023:9942663 (2023). PubMed: 37719786