AB188442

Anti-TMEM56抗体- C-terminal

Name: TMEM56抗体- C-terminal (ab188442)| Abcam中文官网
Brand: Abcam Limited
SKU: AB188442
Price: 5930 CNY
Availability: InStock
Rating: 4 (1 reviews)

Anti-TMEM56 antibody - C-terminal

(1 Review)

(1 Publication)

Rabbit Polyclonal TMEM56 antibody. C-terminal. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TLCD4 aa 200 to C-terminus.

查看别名

TMEM56, TLCD4, TLC domain-containing protein 4, Transmembrane protein 56

2 Images

Immunocytochemistry/ Immunofluorescence - Anti-TMEM56 antibody - C-terminal (AB188442)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-TMEM56 antibody - C-terminal (AB188442)

U-2 OS cells stained for TMEM56 (green) using ab188442 at 2 μg/ml in ICC/IF.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM56 antibody - C-terminal (AB188442)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM56 antibody - C-terminal (AB188442)

Immunohistochemical analysis of paraffin embedded Human uterus, pre-menopause tissue labeling TMEM56 with ab188442 at 1/200.

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

反应种属

Human

应用

ICC/IF, IHC-P

applications

免疫原

Recombinant Fragment Protein within Human TLCD4 aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q96MV1

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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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性能和储存信息

形式

Liquid

纯化工艺

Affinity purification Immunogen

存储溶液

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

运输条件

Blue Ice

分装信息

Upon delivery aliquot

储存信息

Avoid freeze / thaw cycle

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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

TMEM56 also known as Transmembrane Protein 56 has a mass of approximately 43 kDa. It functions as a transmembrane protein that spans the cell membrane. The protein participates in cellular signaling by allowing or facilitating interaction across the membrane. TMEM56 is expressed in various tissues including the lungs heart and placenta. Its membrane-spanning capabilities suggest a role in linking extracellular signals to intracellular responses.

Biological function summary

The role of TMEM56 involves regulation of cellular growth and differentiation processes. It may also interact with other membrane-associated proteins as part of the cellular response complex. By engaging in these processes TMEM56 influences important cellular dynamics that maintain tissue homeostasis and proper cellular function.

Pathways

TMEM56 integrates into signal transduction pathways associated with cellular proliferation and differentiation. It participates in the MAPK/ERK pathway which is important for transmitting extracellular signals into cellular responses. In this context TMEM56 interacts with components like MEK and ERK influencing cell fate decisions and responses to external stimuli.

TMEM56 shows an association with certain types of cancer particularly in its involvement in deregulated cell signaling. Alterations in TMEM56 expression levels or function can disrupt normal cellular signaling contributing to oncogenic processes. Additionally altered expression of TMEM56 connects to neurodegenerative disorders possibly through pathways shared with proteins like Tau which is implicated in conditions like Alzheimer’s disease.

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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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靶点信息

See full target information TLCD4

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Nature structural & molecular biology 30:1141-1152 PubMed37386215

2023

Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID.

Applications

Unspecified application

Species

Unspecified reactive species

Andrea Bernardini,Pooja Mukherjee,Elisabeth Scheer,Ivanka Kamenova,Simona Antonova,Paulina Karen Mendoza Sanchez,Gizem Yayli,Bastien Morlet,H T Marc Timmers,László Tora

View all publications

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Anti-TMEM56抗体- C-terminal

Anti-TMEM56 antibody - C-terminal

Immunocytochemistry/ Immunofluorescence - Anti-TMEM56 antibody - C-terminal (AB188442)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM56 antibody - C-terminal (AB188442)