Anti-TIM 1抗体(ab78494)
Key features and details
- Rabbit polyclonal to TIM 1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-TIM 1抗体
参阅全部 TIM 1 一抗 -
描述
兔多克隆抗体to TIM 1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Synthetic peptide, corresponding to a portion of the amino acids 200-300 of Human TIM 1
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阳性对照
- Testis tissue
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: 0.05% BSA, PBS -
Concentration information loading... -
纯度
Protein G purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab78494于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | (1) |
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 39 kDa.
|
| IHC-P | (1) |
Use a concentration of 2.5 - 5 µg/ml.
|
| 说明 |
|---|
|
WB
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 39 kDa. |
|
IHC-P
Use a concentration of 2.5 - 5 µg/ml. |
靶标
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功能
May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. -
组织特异性
Widely expressed, with highest levels in kidney and testis. Expressed by activated CD4+ T-cells during the development of helper T-cells responses. -
序列相似性
Belongs to the immunoglobulin superfamily. TIM family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 26762 Human
- Entrez Gene: 171283 Mouse
- Omim: 606518 Human
- SwissProt: Q96D42 Human
- SwissProt: Q5QNS5 Mouse
- Unigene: 129711 Human
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别名
- CD365 antibody
- HAVCR 1 antibody
- HAVCR antibody
see all
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TIM 1 antibody (ab78494)Image is courtesy of an anonymous AbReview.
Immunohistochemical analysis of Formaldehyde-fixed murine obese nephric tissue sections, labelling TIM 1 with ab78494 at a dilution of 1/2500 incubated for 12 hours at 4°C in PBS and 2.5% Horse serum. Heat mediated antigen retrival was with Citrate buffer. Blocking was with 2.5% horse serum incubated for 1 hour at 25°C. Secondary was a horse anti-rabbit polyclonal HRP conjugate used undiluted. Counterstaining against nuclear DNA was with DAPI.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TIM 1 antibody (ab78494)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue, staining TIM 1 with ab78494 at 5 µg/ml. -
Western blot - Anti-TIM 1 antibody (ab78494)All lanes : Anti-TIM 1 antibody (ab78494) at 3 µg/ml
Lane 1 : Human brain lysate
Lane 2 : Human brain lysate in presence of immunizing peptide
Lane 3 : Mouse brain lysate
Predicted band size: 39 kDa
数据表及文件
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Datasheet download
文献 (15)
ab78494 被引用在 15 文献中.
- Huang Q et al. Passively-targeted mitochondrial tungsten-based nanodots for efficient acute kidney injury treatment. Bioact Mater 21:381-393 (2023). PubMed: 36185743
- Permyakova A et al. Renal Endocannabinoid Dysregulation in Obesity-Induced Chronic Kidney Disease in Humans. Int J Mol Sci 24:N/A (2023). PubMed: 37686443
- Wu C et al. The Effects of IL-23/IL-18-Polarized Neutrophils on Renal Ischemia-Reperfusion Injury and Allogeneic-Skin-Graft Rejection in Mice. Biomedicines 11:N/A (2023). PubMed: 38137369
- Mao H et al. Fucoxanthin Attenuates Oxidative Damage by Activating the Sirt1/Nrf2/HO-1 Signaling Pathway to Protect the Kidney from Ischemia-Reperfusion Injury. Oxid Med Cell Longev 2022:7444430 (2022). PubMed: 35126819
- Hou B et al. Cpd-42 protects against calcium oxalate nephrocalcinosis-induced renal injury and inflammation by targeting RIPK3-mediated necroptosis. Front Pharmacol 13:1041117 (2022). PubMed: 36408256
