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AB198738

Anti-Thymosin beta 10抗体- C-terminal

Anti-Thymosin beta 10 antibody - C-terminal

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(1 Publication)

Rabbit Polyclonal Thymosin beta 10 antibody. C-terminal. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human TMSB10.

查看别名

PTMB10, THYB10, TMSB10, Thymosin beta-10

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thymosin beta 10 antibody - C-terminal (AB198738)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thymosin beta 10 antibody - C-terminal (AB198738)

Immunohistochemical analysis of Paraffin-embedded Human cervical cancer tissue labeling Thymosin beta 10 with ab198738 at 1/15 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thymosin beta 10 antibody - C-terminal (AB198738)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thymosin beta 10 antibody - C-terminal (AB198738)

Immunohistochemical analysis of Paraffin-embedded Human tonsil cancer tissue labeling Thymosin beta 10 with ab198738 at 1/15 dilution.

关键信息

宿主种属

Rabbit

克隆

Polyclonal

亚型

IgG

不含载体蛋白

No

反应种属

Human

应用

IHC-P

applications

免疫原

Synthetic Peptide within Human TMSB10. The exact immunogen used to generate this antibody is proprietary information.

P63313

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替代产品

Primary Antibodies

AB14338

Anti-Thymosin beta 10 antibody

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搭配使用产品

Primary Antibodies

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Anti-Thymosin beta 4 antibody

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Primary Antibodies

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Anti-Thrombospondin 1 antibody [EPR22927-54]

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Primary Antibodies

AB268020

Anti-Fibronectin antibody [EPR23110-46]

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Fibronectin antibody [EPR23110-46] (AB268020)

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Primary Antibodies

AB133543

Anti-Liver Arginase antibody [EPR6672(B)]

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Liver Arginase antibody [EPR6672(B)] (AB133543)

  • 5
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反应性数据

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/25 - 1/100", "IHCP-species-notes": "<p></p>" } } }
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性能和储存信息

形式
Liquid
纯化工艺
Affinity purification Immunogen
存储溶液
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
运输条件
Blue Ice
推荐的短期储存时间
1-2 weeks
推荐的短期储存条件
+4°C
推荐的长期储存条件
-20°C
分装信息
Upon delivery aliquot
储存信息
Avoid freeze / thaw cycle
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补充信息

This supplementary information is collated from multiple sources and compiled automatically.

Thymosin beta 10 also known as TMSB10 is a small protein that plays a role in the dynamics of the cytoskeleton. It has a mass of approximately 5 kDa. TMSB10 is found in various tissues with high expression levels in the brain kidney and heart. Its function involves binding to actin monomers preventing polymerization and consequently regulating actin filament assembly in cells.
Biological function summary

TMSB10 significantly influences cell movement and proliferation. It serves as an actin-sequestering protein and is not generally part of a larger protein complex. TMSB10 promotes cell motility and plays an essential part in processes like wound healing and angiogenesis. Through these actions it helps in tissue regeneration and repair influencing the cell's structural organization and signaling.

Pathways

TMSB10 is involved in the actin cytoskeleton pathway and cellular signaling pathways that govern movement and shape changes in cells. Its interaction with actin places it in relation to actin-related protein (ARP) complexes such as Arp2/3 which facilitate actin filament branching. In addition TMSB10's regulation of actin dynamics links it to pathways involving proteins like cofilin which modulates actin filament turnover.

TMSB10 shows a connection to cancer and cardiovascular disorders. Elevated levels of TMSB10 have been associated with tumor progression due to its role in enhancing cell movement and metastasis. In cardiovascular disorders changes in TMSB10 expression can impact cardiac function due to its influence on actin dynamics. Proteins such as vascular endothelial growth factor (VEGF) interact with TMSB10 during pathological conditions further illustrating its role in disease mechanisms.
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产品实验方案

For this product, it's our understanding that no specific protocols are required. You can visit:
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靶点信息

Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
See full target information TMSB10
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

PeerJ 11:e14850 PubMed36793891

2023

Abnormal expression of induces intravillous vascularization dysplasia in ectopic pregnancy.

Applications

Unspecified application

Species

Unspecified reactive species

Qian Zhu,Xiaoya Zhao,Duo Zhang,Wei Xia,Jian Zhang
View all publications
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