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Signal Transduction Cytoskeleton / ECM Cytoskeleton Microfilaments Actin etc Actin Binding Proteins

Anti-Thymosin beta 10抗体(ab14338)

  • Datasheet
Reviews (1) Submit a question References (6)

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Key features and details

  • Rabbit polyclonal to Thymosin beta 10
  • Suitable for: ELISA
  • Reacts with: Human
  • Isotype: IgG

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概述

  • 产品名称

    Anti-Thymosin beta 10抗体
    参阅全部 Thymosin beta 10 一抗
  • 描述

    兔多克隆抗体to Thymosin beta 10
  • 宿主

    Rabbit
  • 特异性

    Human Thymosin B10 (aa 38-43). No cross reactivities with human Thymosin B4, Thymosin B9, Thymosin B15, Thymosin B4 (aa 1-4) peptide, or Thymosin B4 (aa 1-14).
  • 经测试应用

    适用于: ELISAmore details
  • 种属反应性

    与反应: Human
  • 免疫原

    Synthetic peptide:

    KRSEIS

    conjugated to KLH, corresponding to amino acids 38-43 of Human Thymosin beta 10.
    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • 常规说明

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

性能

  • 形式

    Liquid
  • 存放说明

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液

    Constituent: Whole serum
  • Concentration information loading...
  • 纯度

    Whole antiserum
  • 克隆

    多克隆
  • 同种型

    IgG
  • 研究领域

    • Signal Transduction
    • Cytoskeleton / ECM
    • Cytoskeleton
    • Microfilaments
    • Actin etc
    • Actin Binding Proteins

相关产品

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human Thymosin beta 10 protein (ab132133)

应用

The Abpromise guarantee

Abpromise™承诺保证使用ab14338于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

应用 Ab评论 说明
ELISA
1/4000.
说明
ELISA
1/4000.

靶标

  • 功能

    Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
  • 序列相似性

    Belongs to the thymosin beta family.
  • 发展阶段

    Found to decrease dramatically after birth.
  • 细胞定位

    Cytoplasm > cytoskeleton.
  • Target information above from: UniProt accession P63313 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • 数据库链接

    • Entrez Gene: 9168 Human
    • Omim: 188399 Human
    • SwissProt: P63313 Human
    • Unigene: 446574 Human
    • 别名

      • MIG 12 antibody
      • MIG12 antibody
      • Migration inducing gene 12 antibody
      • Migration inducing protein 12 antibody
      • Ptmb10 antibody
      • TB 10 antibody
      • TB10 antibody
      • Thyb 10 antibody
      • Thyb10 antibody
      • Thymosin beta-10 antibody
      • Tmsb10 antibody
      • TYB10_HUMAN antibody
      see all

    实验方案

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    数据表及文件

    • Datasheet download

      Download

    文献 (6)

    发表研究结果有使用 ab14338?请让我们知道,以便我们可以引用本数据表中的参考文章。

    ab14338 被引用在 6 文献中.

    • Pan Q  et al. TMSB10 acts as a biomarker and promotes progression of clear cell renal cell carcinoma. Int J Oncol 56:1101-1114 (2020). PubMed: 32319572
    • Wang B  et al. Overexpression of thymosin ß10 correlates with disease progression and poor prognosis in bladder cancer. Exp Ther Med 18:3759-3766 (2019). PubMed: 31616507
    • Zhang W  et al. Deer thymosin beta 10 functions as a novel factor for angiogenesis and chondrogenesis during antler growth and regeneration. Stem Cell Res Ther 9:166 (2018). PubMed: 29921287
    • Marthandan S  et al. Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts. Biomed Res Int 2015:731938 (2015). WB . PubMed: 26339636
    • Lagarrigue M  et al. Revisiting Rat Spermatogenesis with MALDI Imaging at 20-{micro}m Resolution. Mol Cell Proteomics 10:M110.005991 (2011). IHC-P ; Rat . PubMed: 21149303
    • Zhang T  et al. Overexpression of thymosin beta-10 inhibits VEGF mRNA expression, autocrine VEGF protein production, and tube formation in hypoxia-induced monkey choroid-retinal endothelial cells. Ophthalmic Res 41:36-43 (2009). WB ; Human . PubMed: 18854659

    客户评价及客户问答

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    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) abreview for Anti-Thymosin beta 10 antibody

    Good
    Abreviews
    Abreviews
    abreview image
    Application
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Sample
    Human Tissue sections (breast)
    Specification
    breast
    Fixative
    Formaldehyde
    Antigen retrieval step
    Heat mediated - Buffer/Enzyme Used: Citrate pH6.0
    Permeabilization
    No
    Blocking step
    Serum as blocking agent for 10 minute(s) · Concentration: 1.5%
    Read More
    The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

    Abcam user community

    Verified customer

    提交于 Jan 03 2008

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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