Anti-Thrombopoietin抗体[1B11] (ab128487)
Key features and details
- Mouse monoclonal [1B11] to Thrombopoietin
- Suitable for: WB, ELISA, Flow Cyt
- Reacts with: Human, Recombinant fragment
- Isotype: IgG2a
概述
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产品名称
Anti-Thrombopoietin抗体[1B11]
参阅全部 Thrombopoietin 一抗 -
描述
小鼠单克隆抗体[1B11] to Thrombopoietin -
宿主
Mouse -
经测试应用
适用于: WB, ELISA, Flow Cytmore details -
种属反应性
与反应: Human, Recombinant fragment -
免疫原
Recombinant fragment corresponding to Human Thrombopoietin aa 250-303.
Database link: P40225 -
阳性对照
- Human Thrombopoietin (amino acids 250-303) recombinant protein; MCF7 cells
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.05% Sodium azide
Constituent: 99% PBS
Contains 0.5% protein stabilizer -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
Purified from tissue culture supernatant. -
克隆
单克隆 -
克隆编号
1B11 -
同种型
IgG2a -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab128487于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/2000. Predicted molecular weight: 37 kDa.
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|
ELISA |
1/10000.
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|
Flow Cyt |
1/200 - 1/400.
ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
说明 |
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WB
1/500 - 1/2000. Predicted molecular weight: 37 kDa. |
ELISA
1/10000. |
Flow Cyt
1/200 - 1/400. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. -
疾病相关
Defects in THPO are a cause of essential thrombocythemia (ET) [MIM:187950]. ET is inherited as an autosomal dominant trait which is characterized by elevated platelet levels due to sustained proliferation of megakaryocytes, and frequently lead to thrombotic and haemorrhagic complications. -
序列相似性
Belongs to the EPO/TPO family. -
结构域
Two-domain structure with an erythropoietin-like N-terminal and a Ser/Pro/Thr-rich C-terminal. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 7066 Human
- Omim: 600044 Human
- SwissProt: P40225 Human
- Unigene: 1166 Human
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别名
- C mpl ligand antibody
- C-mpl ligand antibody
- Megakaryocyte colony stimulating factor antibody
see all
图片
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ab128487, at a 1/200 dilution, staining Thrombopoietin in MCF7 cells by Flow Cytometry (green). Negative control is shown in red.
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ELISA using ab128487.
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Anti-Thrombopoietin antibody [1B11] (ab128487) at 1/500 dilution + Human Thrombopoietin (amino acids 250-303) recombinant protein
Predicted band size: 37 kDa
Expected MWt of recombinant protein is 30 kDa.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab128487 尚未被引用在任何文献中。