Anti-Thomsen-Friedenreich Antigen抗体[SPM320]，prediluted (ab17785)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thomsen-Friedenreich Antigen antibody [SPM320], prediluted (ab17785)](https://www.abcam.cn/ps/products/17/ab17785/Images/ab17785-26579-anti-thomsen-friedenreich-antigen-antibody-spm320-prediluted-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thomsen-Friedenreich Antigen antibody [SPM320], prediluted (ab17785)")
Key features and details
- Mouse monoclonal [SPM320] to Thomsen-Friedenreich Antigen, prediluted
- Suitable for: IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgM
概述
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产品名称
Anti-Thomsen-Friedenreich Antigen抗体[SPM320]，prediluted
参阅全部 Thomsen-Friedenreich Antigen 一抗 -
描述
小鼠单克隆抗体[SPM320] to Thomsen-Friedenreich Antigen，prediluted -
宿主
Mouse -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Tissue, cells or virus corresponding to Human Thomsen-Friedenreich Antigen.
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表位
Galß1-3GalNAc -
阳性对照
- KG1 cells. Human colorectal carcinoma tissues.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: Tris buffered saline, 1% BSA -
Concentration information loading... -
纯度
Purified IgM -
克隆
单克隆 -
克隆编号
SPM320 -
同种型
IgM -
轻链类型
kappa -
研究领域
相关产品
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Compatible Secondaries
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab17785于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P |
Use at an assay dependent concentration. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 说明 |
|---|
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IHC-P
Use at an assay dependent concentration. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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相关性
The Thomsen Friedenreich antigen acts as an oncofoetal antigen, with low expression in normal adult tissues but increasing to foetal levels of expression in hyperplasia or malignancy. It is considered as a pan carcinoma marker. Can be applied for the detection of cells with TF antigen and is especially applicable for sensitive determination of neuraminidases. -
细胞定位
Cell Membrane -
别名
- CD176 antibody
- TF antibody
- TF antigen antibody
图片
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thomsen-Friedenreich Antigen antibody [SPM320], prediluted (ab17785)Human colon adenocarcinoma stained with ab17785 (prediluted)
数据表及文件
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Datasheet download
文献 (3)
ab17785 被引用在 3 文献中.
- Saha S et al. Mangiferin attenuates oxidative stress induced renal cell damage through activation of PI3K induced Akt and Nrf-2 mediated signaling pathways. Biochem Biophys Rep 5:313-327 (2016). PubMed: 28955838
- Bhattacharyya S et al. Amelioration of aspirin induced oxidative impairment and apoptotic cell death by a novel antioxidant protein molecule isolated from the herb Phyllanthus niruri. PLoS One 9:e89026 (2014). Mouse . PubMed: 24586486
- Kumagai H et al. Multifunctional nanobeacon for imaging Thomsen-Friedenreich antigen-associated colorectal cancer. Int J Cancer : (2012). Human . PubMed: 23055136
