Anti-TGF beta 2抗体(ab80059)
Key features and details
- Rabbit polyclonal to TGF beta 2
- Suitable for: IHC, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TGF beta 2抗体
参阅全部 TGF beta 2 一抗 -
描述
兔多克隆抗体to TGF beta 2 -
宿主
Rabbit -
特异性
Reacts specifically with human 48 kDa TGF beta 2 protein. -
经测试应用
适用于: IHC, WBmore details -
种属反应性
与反应: Human
预测可用于: a wide range of other species
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免疫原
Synthetic peptide derived from the N terminal domain of Human TGF beta 2.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Constituent: Whole serum -
Concentration information loading... -
纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab80059于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC |
1/100 - 1/500.
|
|
| WB | (1) |
1/500 - 1/5000. Predicted molecular weight: 47 kDa.
|
| 说明 |
|---|
|
IHC
1/100 - 1/500. |
|
WB
1/500 - 1/5000. Predicted molecular weight: 47 kDa. |
靶标
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功能
TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. -
疾病相关
A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9.
Loeys-Dietz syndrome 4
Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). NSAD is a frequently asymptomatic but potentially lethal disease characterized by thoracic aortic aneurysms and dissections without additional syndromic features. -
序列相似性
Belongs to the TGF-beta family. -
翻译后修饰
The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 7040 Human
- Entrez Gene: 7042 Human
- Entrez Gene: 7043 Human
- Omim: 190220 Human
- SwissProt: P01137 Human
- SwissProt: P10600 Human
- SwissProt: P61812 Human
- Unigene: 133379 Human
see all -
别名
- BSC-1 cell growth inhibitor antibody
- BSC1 cell growth inhibitor antibody
- Cetermin antibody
see all
数据表及文件
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Datasheet download
文献 (2)
ab80059 被引用在 2 文献中.
- Chuo D et al. LncRNA MIR503HG is downregulated in Han Chinese with colorectal cancer and inhibits cell migration and invasion mediated by TGF-ß2. Gene 713:143960 (2019). PubMed: 31278965
- Nicola T et al. Hypoxia-induced inhibition of lung development is attenuated by the peroxisome proliferator-activated receptor-{gamma} agonist rosiglitazone. Am J Physiol Lung Cell Mol Physiol 301:L125-34 (2011). WB ; Mouse . PubMed: 21531777
