Anti-Tetanus Toxin抗体(ab53829)
Key features and details
- Rabbit polyclonal to Tetanus Toxin
- Suitable for: WB, ELISA
- Isotype: IgG
概述
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产品名称
Anti-Tetanus Toxin抗体
参阅全部 Tetanus Toxin 一抗 -
描述
兔多克隆抗体to Tetanus Toxin -
宿主
Rabbit -
经测试应用
适用于: WB, ELISAmore details -
种属反应性
与反应: Clostridium tetani -
免疫原
Tissue, cells or virus corresponding to Tetanus Toxin. Tetanus toxoid (formaldehyde inactivated tetanus toxin).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.098% Sodium azide
Constituent: Whole serum -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab53829于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent dilution. Predicted molecular weight: 150 kDa.
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ELISA |
Use at an assay dependent dilution.
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说明 |
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WB
Use at an assay dependent dilution. Predicted molecular weight: 150 kDa. |
ELISA
Use at an assay dependent dilution. |
靶标
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相关性
Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation. -
细胞定位
Secreted -
别名
- Tentoxylysin antibody
- Tetanus toxin chain H antibody
- Tetanus toxin chain L antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab53829 被引用在 2 文献中.
- Chai P et al. The recombinant protein combined vaccine based on the fragment C of tetanus toxin and the cross-reacting material 197. Appl Microbiol Biotechnol 105:1683-1692 (2021). PubMed: 33511443
- Mittal AM et al. Multiple network properties overcome random connectivity to enable stereotypic sensory responses. Nat Commun 11:1023 (2020). PubMed: 32094345