Anti-Tensin 3抗体(ab178554)
Key features and details
- Rabbit polyclonal to Tensin 3
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human, African green monkey
- Isotype: IgG
概述
-
产品名称
Anti-Tensin 3抗体 -
描述
兔多克隆抗体to Tensin 3 -
宿主
Rabbit -
经测试应用
适用于: ICC/IF, IHC-Pmore details -
种属反应性
与反应: Human, African green monkey -
免疫原
Synthetic peptide corresponding to Human Tensin 3 (internal sequence).
Database link: Q68CZ2 -
阳性对照
- Human heart tissue; COS7 cells.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
PBS without Mg2+ and Ca2+ -
Concentration information loading... -
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab178554于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC/IF |
1/100 - 1/500.
|
|
| IHC-P |
1/50 - 1/100.
|
| 说明 |
|---|
|
ICC/IF
1/100 - 1/500. |
|
IHC-P
1/50 - 1/100. |
靶标
-
功能
May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development. -
组织特异性
Expressed in umbilical vein endothelial cells, epithelial cells, and fibroblasts cells (at protein level). Highly expressed in thyroid, kidney and placenta. Low expression in heart, skeletal muscle, spleen, liver, and lung. Expressed in tumor endothelial cells. Expression seems to be down-regulated in thyroid tumor tissues and in anaplastic carcinomas. -
序列相似性
Contains 1 C2 tensin-type domain.
Contains 1 phosphatase tensin-type domain.
Contains 1 SH2 domain. -
翻译后修饰
EGF/epidermal growth factor induces tyrosine phosphorylation in a time- and dose-dependent manner. -
细胞定位
Cell junction, focal adhesion. - Information by UniProt
-
数据库链接
- Entrez Gene: 64759 Human
- Omim: 606825 Human
- SwissProt: Q68CZ2 Human
- Unigene: 520814 Human
-
别名
- TEM 6 antibody
- TEM6 antibody
- TENS 1 antibody
see all
图片
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Tensin 3 antibody (ab178554)
Immunohistochemical analysis of paraffin-embedded Human heart tissue labeling Tensin 3 with ab178554 at 1/50 dilution in the presence (right panel) or absence (left panel) of immunizing peptide.
-
Immunocytochemistry/ Immunofluorescence - Anti-Tensin 3 antibody (ab178554)Immunofluorescent analysis of COS7 cells labeling Tensin 3 with ab178554 at 1/100 dilution in the presence (right panel) or absence (left panel) of immunizing peptide.
实验方案
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab178554 尚未被引用在任何文献中。