Anti-TCP1 delta抗体
Anti-TCP1 delta antibody
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(1 Publication)
Rabbit Polyclonal TCP1 delta antibody. Suitable for IP, WB and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human CCT4 aa 1-50.
查看别名
CCTD, SRB, CCT4, T-complex protein 1 subunit delta, TCP-1-delta, CCT-delta, Chaperonin containing T-complex polypeptide 1 subunit 4, Stimulator of TAR RNA-binding
- IP
Supplier Data
Immunoprecipitation - Anti-TCP1 delta antibody (AB264353)
TCP1 delta was immunoprecipitated from 1mg of HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate with ab264353 at 6 μg per reaction. Western blot was performed from the immunoprecipitate using ab264353 at 0.1 μg/ml.
Lane 1 : ab264353 IP in HEK-293T whole cell lysate.
Lane 2 : Control IgG.
Exposure time : 10 secs.
Cells prepared using NETN lysis buffer.
All lanes:
Immunoprecipitation - Anti-TCP1 delta antibody (ab264353)
Predicted band size: 60 kDa
false
- WB
Supplier Data
Western blot - Anti-TCP1 delta antibody (AB264353)
Cells prepared using NETN lysis buffer.
All lanes:
Western blot - Anti-TCP1 delta antibody (ab264353) at 0.1 µg/mL
Lane 1:
HeLa (Human epithelial cell line from cervix adenocarcinoma) whole cell lysate at 50 µg
Lane 2:
HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate at 50 µg
Lane 3:
Jurkat (Human T cell leukemia cell line from peripheral blood) whole cell lysate at 50 µg
Lane 4:
TCMK (Mouse kidney epithelial cell line) whole cell lysate at 50 µg
Lane 5:
NIH/3T3 (Mouse embryo fibroblast cell line) whole cell lysate at 50 µg
Predicted band size: 60 kDa
false
Exposure time: 10s
反应性数据
性能和储存信息
形式
纯化工艺
存储溶液
运输条件
推荐的短期储存时间
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
TCP1 delta functions as part of the chaperonin complex assisting in the folding of cytoskeletal proteins such as actin and tubulin. This complex is critical for maintaining cellular integrity and function by ensuring proper protein configuration. TCP1 delta influences cell cycle regulation and proliferation through its role in folding key components of the cytoskeleton. Formation of this complex occurs in the cytoplasm where it effectively brings together other subunits to undertake its biological roles.
Pathways
TCP1 delta interacts significantly in the protein folding and cytoskeleton organization pathways. It collaborates with other proteins like CCT1 and CCT5 within the TCP-1 ring complex ensuring accurate protein assembly. The protein folding pathway where TCP1 delta operates is essential for cell cycle progression and maintaining cellular homeostasis while also playing a role in the signal transduction involving the cytoskeleton.
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靶点信息
文献 (1)
Recent publications for all applications. Explore the full list and refine your search
Chinese medical journal 134:2721-2729 PubMed34732665
2021
Applications
Unspecified application
Species
Unspecified reactive species
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