Anti-TBCD/SSD1抗体(ab72624)
Key features and details
- Mouse polyclonal to TBCD/SSD1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TBCD/SSD1抗体
参阅全部 TBCD/SSD1 一抗 -
描述
小鼠多克隆抗体to TBCD/SSD1 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein within Human TBCD/SSD1. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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阳性对照
- TBCD/SSD1 transfected 293T cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.4
Constituent: PBS -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab72624于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 75 kDa (predicted molecular weight: 133 kDa).
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| 说明 |
|---|
|
WB
1/500 - 1/1000. Detects a band of approximately 75 kDa (predicted molecular weight: 133 kDa). |
靶标
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功能
Tubulin-folding protein; involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Acts as a GTPase-activating protein (GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane. -
组织特异性
Ubiquitously expressed. -
序列相似性
Belongs to the TBCD family.
Contains 3 HEAT repeats. -
细胞定位
Cell junction > tight junction. Lateral cell membrane. Cytoplasm. Cell junction > adherens junction. Localized in cell-cell contacts. - Information by UniProt
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数据库链接
- Entrez Gene: 6904 Human
- Omim: 604649 Human
- SwissProt: Q9BTW9 Human
- Unigene: 728173 Human
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别名
- Beta tubulin cofactor D antibody
- Beta-tubulin cofactor D antibody
- KIAA0988 antibody
see all
图片
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Western blot - Anti-TBCD/SSD1 antibody (ab72624)All lanes : Anti-TBCD/SSD1 antibody (ab72624) at 1/500 dilution
Lane 1 : TBCD/SSD1 transfected 293T cell lystae
Lane 2 : Non transfected 293T cell lystae
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG(H&L)-HRP Conjugate at 1/25000 dilution
Predicted band size: 133 kDa
Observed band size: 75 kDa why is the actual band size different from the predicted?
数据表及文件
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Datasheet download
文献 (0)
ab72624 尚未被引用在任何文献中。
