Anti-TAGLN2抗体
Anti-TAGLN2 antibody
5
(1 Review)
|
(12 Publications)
Rabbit Polyclonal TAGLN2 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human, Mouse, Rat samples. Cited in 12 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TAGLN2 aa 1-150.
查看别名
KIAA0120, CDABP0035, TAGLN2, Transgelin-2, Epididymis tissue protein Li 7e, SM22-alpha homolog
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TAGLN2 antibody (AB121146)
Immunohistochemical staining of Human bone marrow with ab121146 at 1/500 dilution.
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-TAGLN2 antibody (AB121146)
Immunofluorescent staining of Human cell line U-2 OS shows positivity in cytoskeleton (actin filaments). Recommended concentration of ab121146 1-4 µg/ml. Cells treated with PFA/Triton X-100.
- WB
Supplier Data
Western blot - Anti-TAGLN2 antibody (AB121146)
Lane 1:
Western blot - Anti-TAGLN2 antibody (ab121146)
Lane 2:
Western blot - Anti-TAGLN2 antibody (ab121146) at 0.4 µg/mL
All lanes:
A431 cells
Predicted band size: 22 kDa
false
- WB
Supplier Data
Western blot - Anti-TAGLN2 antibody (AB121146)
All lanes:
Western blot - Anti-TAGLN2 antibody (ab121146) at 0.4 µg/mL
Lane 1:
NIH/3T3 cells
Lane 2:
NBT-II cells
Predicted band size: 22 kDa
false
反应性数据
性能和储存信息
形式
纯化工艺
存储溶液
运输条件
推荐的短期储存条件
推荐的长期储存条件
分装信息
储存信息
补充信息
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The protein aids in maintaining cell structure and facilitates cell movement and adhesion. TAGLN2 is a monomer and does not form complexes but interacts closely with actin to regulate cytoskeletal processes. It acts as a modulator of actin filament organization which impacts cellular responses. The protein supports processes such as wound healing and embryonic development by influencing the migration and invasion of cells.
Pathways
TAGLN2 influences cellular mechanisms related to the actin cytoskeleton structure and dynamics. It plays a role in the Rho signaling pathway which is essential for cytoskeletal rearrangement and maintaining cellular tension. The protein associates with RhoA a small GTPase which is involved in mediating various functions including contractility and motility. Through RhoA TAGLN2 impacts cell morphology and stress fiber formation.
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文献 (12)
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Cell proliferation 58:e13755 PubMed39329203
2024
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iScience 27:109342 PubMed38495819
2024
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Bioengineered 13:11646-11655 PubMed35505656
2022
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Cardiovascular therapeutics 2022:9966306 PubMed35360546
2022
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Frontiers in cell and developmental biology 10:810633 PubMed35281112
2022
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Experimental and therapeutic medicine 22:824 PubMed34149870
2021
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International journal of molecular medicine 48: PubMed33982775
2021
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Experimental cell research 404:112619 PubMed33965400
2021
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Journal of cell science 133: PubMed32467330
2020
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Journal of cellular physiology 234:4910-4923 PubMed30317571
2018
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