Anti-Syndecan 3抗体(ab63932)
Key features and details
- Rabbit polyclonal to Syndecan 3
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术，可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Syndecan 3抗体
参阅全部 Syndecan 3 一抗 -
描述
兔多克隆抗体to Syndecan 3 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat -
免疫原
Synthetic peptide surrounding amino acid 427 of human Syndecan 3
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常规说明
This product is manufactured by BioVision, an Abcam company and was previously called 3824 Syndecan-3 Antibody. 3824-100 is the same size as the 100 µg size of ab63932.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA -
Concentration information loading... -
纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab63932于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB |
Use a concentration of 0.5 - 4 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).
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| 说明 |
|---|
|
WB
Use a concentration of 0.5 - 4 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa). |
靶标
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功能
Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. -
组织特异性
Expressed in the nervous system, the adrenal gland, and the spleen. -
序列相似性
Belongs to the syndecan proteoglycan family. -
翻译后修饰
O-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 116673 Rat
- SwissProt: P33671 Rat
- Unigene: 10504 Rat
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别名
- N-syndecan antibody
- Sdc3 antibody
- SDC3_HUMAN antibody
see all
图片
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Western blot - Anti-Syndecan 3 antibody (ab63932)Anti-Syndecan 3 antibody (ab63932) at 1 µg/ml + Rat kidney tissue lysate at 30 µg
Predicted band size: 46 kDa
Observed band size: 46 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (7)
ab63932 被引用在 7 文献中.
- Assmann AK et al. A Role for Peroxisome Proliferator-Activated Receptor Gamma Agonists in Counteracting the Degeneration of Cardiovascular Grafts. J Cardiovasc Pharmacol 79:e103-e115 (2021). PubMed: 34654784
- Bang ML et al. Glial M6B stabilizes the axonal membrane at peripheral nodes of Ranvier. Glia 66:801-812 (2018). PubMed: 29282769
- Tinholt M et al. Syndecan-3 and TFPI colocalize on the surface of endothelial-, smooth muscle-, and cancer cells. PLoS One 10:e0117404 (2015). PubMed: 25617766
- Coulson-Thomas VJ et al. Loss of corneal epithelial heparan sulfate leads to corneal degeneration and impaired wound healing. Invest Ophthalmol Vis Sci 56:3004-14 (2015). PubMed: 26024086
- Coulson-Thomas VJ et al. Heparan sulfate regulates hair follicle and sebaceous gland morphogenesis and homeostasis. J Biol Chem 289:25211-26 (2014). IHC-FoFr ; Mouse . PubMed: 25053416
- Gordon A et al. Caspr and caspr2 are required for both radial and longitudinal organization of myelinated axons. J Neurosci 34:14820-6 (2014). Mouse . PubMed: 25378149
- Chui A et al. Placental syndecan expression is altered in human idiopathic fetal growth restriction. Am J Pathol 180:693-702 (2012). PubMed: 22138583